Table of Contents 1
Cover
2
PREFACE
5
1 INTRODUCTION
1.1 GENERAL INTRODUCTION
1.2 DEFINITIONS
1.3 GENERAL MICROBIOLOGY
1.4 GENERAL CONSIDERATIONS
FURTHER READING
6
2 PHYSICAL DISINFECTION
2.1 INTRODUCTION
2.2 HEAT
2.3 COLD TEMPERATURES
2.4 RADIATION
2.5 FILTRATION
FURTHER READING
7
3 CHEMICAL DISINFECTION
3.1 INTRODUCTION
3.2 ACIDS AND ACID DERIVATIVES
3.3 ALKALIS (BASES)
3.4 ALDEHYDES
3.5 ALCOHOLS
3.6 ANILIDES
3.7 ANTIMICROBIAL DYES
3.8 BIGUANIDES
3.9 DIAMIDINES
3.10 ESSENTIAL OILS AND PLANT EXTRACTS
3.11 HALOGENS AND HALOGEN-RELEASING AGENTS
3.12 METALS
3.13 PEROXYGENS AND OTHER FORMS OF OXYGEN
3.14 PHENOLICS
3.15 ANTISEPTIC PHENOLICS
3.16 QACS AND OTHER SURFACTANTS
3.17 MISCELLANEOUS BIOCIDES OR APPLICATIONS
FURTHER READING
8
4 ANTISEPTICS AND ANTISEPSIS
4.1 INTRODUCTION
4.2 SOME DEFINITIONS SPECIFIC TO ANTISEPSIS
4.3 THE STRUCTURE OF SKIN
4.4 SKIN MICROBIOLOGY
4.5 ANTISEPTIC APPLICATIONS
4.6 BIOCIDES USED AS ANTISEPTICS
FURTHER READING
9
5 PHYSICAL STERILIZATION
5.1 INTRODUCTION
5.2 STEAM
5.3 DRY-HEAT STERILIZATION
5.4 RADIATION STERILIZATION
5.5 FILTRATION
5.6 DEVELOPING METHODS
FURTHER READING
10
6 CHEMICAL STERILIZATION
6.1 INTRODUCTION
6.2 EPOXIDES
6.3 LTSF
6.4 HIGH-TEMPERATURE FORMALDEHYDE-ALCOHOL
6.5 HYDROGEN PEROXIDE
6.6 OTHER OXIDIZING-AGENT-BASED PROCESSES
FURTHER READING
11
7 MECHANISMS OF ACTION
7.1 INTRODUCTION
7.2 ANTI-INFECTIVES
7.3 MACROMOLECULAR STRUCTURE
7.4 GENERAL MECHANISMS OF ACTION
FURTHER READING
12
8 MECHANISMS OF MICROBIAL RESISTANCE
8.1 INTRODUCTION
8.2 BIOCIDE-MICROORGANISM INTERACTION
8.3 INTRINSIC BACTERIAL RESISTANCE MECHANISMS
8.4 INTRINSIC RESISTANCE OF MYCOBACTERIA
8.5 INTRINSIC RESISTANCE OF OTHER GRAM-POSITIVE BACTERIA
8.6 INTRINSIC RESISTANCE OF GRAM-NEGATIVE BACTERIA
8.7 ACQUIRED BACTERIAL RESISTANCE MECHANISMS
8.8 MECHANISMS OF VIRAL RESISTANCE
8.9 MECHANISMS OF PRION RESISTANCE
8.10 MECHANISMS OF FUNGAL RESISTANCE
8.11 MECHANISMS OF RESISTANCE IN OTHER EUKARYOTIC MICROORGANISMS
FURTHER READING
