on>
Frontiers of Hormone Research
Vol. 50
Series Editor
Ezio Ghigo Turin
Co-Editor
Federica Guaraldi Bologna
Vitamin D in Clinical Medicine
Volume Editors
Andrea Giustina Milan
John P. Bilezikian New York, NY
10 figures, 4 in color, and 14 tables, 2018
Frontiers of Hormone Research
Founded 1972 by Tj.B. van Wimersma Greidanus, Utrecht
Continued by Ashley B. Grossman, Oxford (1996–2013)
| _______________________Andrea Giustina, MDChair of Endocrinology and MetabolismSan Raffaele University HospitalMilan (Italy) | _______________________John P. Bilezikian, MDDepartment of Medicine/EndocrinologyColumbia UniversityNew York, NY (USA) |
Library of Congress Cataloging-in-Publication Data
Names: Giustina, Andrea, editor. | Bilezikian, John P., editor.
Title: Vitamin D in clinical medicine / volume editors, Andrea Giustina, John P. Bilezikian.
Other titles: Frontiers of hormone research ; v. 50. 0301-3073
Description: Basel ; New York : Karger, 2018. | Series: Frontiers of hormone research, ISSN 0301-3073 ; vol. 50 | Includes bibliographical references and indexes.
Identifiers: LCCN 2018007523| ISBN 9783318063387 (alk. paper) | ISBN 9783318063394 (e-ISBN)
Subjects: | MESH: Vitamin D Deficiency--complications | Vitamin D--metabolism | Endocrine System Diseases--etiology
Classification: LCC QP772.V53 | NLM WD 145 | DDC 615.3/28--dc23 LC record available at
https://lccn.loc.gov/2018007523
Bibliographic Indices. This publication is listed in bibliographic services, including Current Contents® and PubMed/MEDLINE.
Disclaimer. The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the book is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
© Copyright 2018 by S. Karger AG, P.O. Box, CH–4009 Basel (Switzerland)
Printed on acid-free and non-aging paper (ISO 9706)
ISSN 0301–3073
e-ISSN 1662–3762
ISBN 978–3–318–06338–7
e-ISBN 978–3–318–06339–4
Contents
Vitamin D: A Key Player in Clinical Medicine
Giustina, A. (Milan); Bilezikian, J.P. (New York, NY)
Physiology of the Calcium-Parathyroid Hormone-Vitamin D Axis
Goltzman, D. (Montreal, QC); Mannstadt, M. (Boston, MA); Marcocci, C. (Pisa)
Bikle, D.D. (San Francisco, CA)
Vilaça, T. (Sheffield); Lazaretti-Castro, M. (São Paulo)
New Concepts in Vitamin D Requirements for Children and Adolescents: A Controversy Revisited
Laing, E.M.; Lewis, R.D. (Athens, GA)
Practical Issues in Vitamin D Replacement
Adler, R.A. (Richmond, VA)
Extra-Skeletal Effects of Vitamin D
Bouillon, R. (Leuven)
Hypercalcemic States Associated with Abnormalities of Vitamin D Metabolism
Jones, G. (Kingston, ON); Schlingmann, K.-P. (Munster)
Vitamin D and Hypoparathyroidism
Bandeira, L.C.; Rubin, M.R.; Cusano, N.E.; Bilezikian, J.P. (New York, NY)
Vitamin D and Primary Hyperparathyroidism
Walker, M.D. (New York, NY); Bollerslev, J. (Oslo)
Vitamin D and Secondary Hyperparathyroid States
Cipriani, C.; Pepe, J.; Colangelo, L.; Minisola, S. (Rome)
Vitamin D and Glucocorticoid-Induced Osteoporosis
Mazziotti, G. (Mantua); Formenti, A.M. (Brescia); Frara, S.; Doga, M.; Giustina, A. (Milan)
Vitamin D and Diabetes Mellitus
Maddaloni, E.; Cavallari, I.; Napoli, N. (Rome); Conte, C. (Milan)
Vitamin D, Sarcopenia and Aging
Skaaby, T.; Thuesen, B.H. (Glostrup); Linneberg, A. (Glostrup/Copenhagen)