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Vaccines for Older Adults:
Current Practices and Future Opportunities
Interdisciplinary Topics in
Gerontology and Geriatrics
Vol. 43
Series Editor
Tamas Fulop Sherbrooke, QC
Vaccines for Older Adults: Current Practices and Future Opportunities
Volume Editor
Birgit Weinberger Innsbruck
17 figures, 9 in color, and 11 tables, 2020
_______________________Birgit WeinbergerInstitute for Biomedical Aging ResearchUniversity InnsbruckRennweg 10AT–6020 Innsbruck (Austria) |
Library of Congress Cataloging-in-Publication Data
Names: Weinberger, Birgit, editor.
Title: Vaccines for older adults : current practices and future opportunities / volume editor, Birgit Weinberger.
Other titles: Interdisciplinary topics in gerontology and geriatrics ; v. 43. 2297-3508
Description: Basel ; New York : Karger, 2020. | Series: Interdisciplinary topics in gerontology and geriatrics, 2297-3508 ; vol. 43 | Includes bibliographical references and index. | Summary: “This book summarizes age-related changes of the immune system and their impact on immune responses to vaccination, as well as other factors influencing vaccine-induced immune responses in old age. It gives an overview of vaccines which are currently available for older adults and of novel technologies and targets which hopefully will lead to more and improved vaccines for this vulnerable population”-- Provided by publisher.
Identifiers: LCCN 2019059866 | ISBN 9783318066777 (hardcover ; alk. paper) | ISBN 9783318066784 (ebook)
Subjects: MESH: Vaccines | Aged | Vaccination | Immunity--physiology | Aging--physiology | Age Factors
Classification: LCC QR189 | NLM W1 IN679 v.43 2020 | DDC 615.3/72--dc23
LC record available at https://lccn.loc.gov/2019059866
Bibliographic Indices. This publication is listed in bibliographic services, including Current Contents® and PubMed/MEDLINE.
Disclaimer. The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the book is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
© Copyright 2020 by S. Karger AG, P.O. Box, CH–4009 Basel (Switzerland)
Printed on acid-free and non-aging paper (ISO 9706)
ISSN 2297–3508
e-ISSN 2297–3486
ISBN 978–3–318–06677–7
e-ISBN 978–3–318–06678–4
Contents
Weinberger, B. (Innsbruck)
Immunosenescence and Other Risk Factors Affecting Vaccination Success in Old Age
How Inflammation Blunts Innate Immunity in Aging
Goldberg, E.L.; Shaw, A.C.; Montgomery, R.R. (New Haven, CT)
Natural Killer Cells, Aging, and Vaccination
Witkowski, J.M. (Gdansk); Larbi, A. (Singapore/Tunis); Le Page, A.; Fülöp, T. (Sherbrooke, QC)
Changes in T Cell Homeostasis and Vaccine Responses in Old Age
Wong, G.C.L. (Singapore); Strickland, M.C. (Singapore/Southhampton); Larbi, A. (Singapore/Sherbrooke, QC/Tunis)
Age-Related Changes in B Cells Relevant to Vaccine Responses
Dunn-Walters, D.K.; Stewart, A.T.; Sinclair, E.L.; Serangeli, I. (Guildford)
Comorbidities in the Elderly and Their Possible Influence on Vaccine Response
Kwetkat, A. (Jena); Heppner, H.J. (Witten/Schwelm)
The Impact of Obesity and Metabolic Syndrome on Vaccination Success
Frasca, D.; Blomberg, B.B. (Miami, FL)
Current Vaccines for the Older Population
Influenza Vaccination: Accelerating the Process for New Vaccine Development in Older Adults
McElhaney, J.E. (Sudbury, ON); Andrew, M.K. (Halifax, NS); Haynes, L.; Kuchel, G.A. (Farmington, CT); McNeil, S.A. (Halifax, NS); Pawelec, G. (Sudbury, ON/Tübingen)
Vaccines to Protect Older Adults against Pneumococcal Disease
van de Garde, M.D.B.; Knol, M.J.; Rots, N.Y.; van Baarle, D.; van Els, C.A.C.M. (Bilthoven)
Herpes Zoster and Its Prevention by Vaccination
Johnson, R.W. (Bristol); Levin, M.J. (Aurora, CO)
Weinberger, B. (Innsbruck)
Jilg, W. (Regensburg)