Группа авторов

Patty's Industrial Hygiene, Physical and Biological Agents


Скачать книгу

0.00990 266 91.9 0.01088 290 84.3 0.01186 243 100.6 0.00994 267 91.6 0.01092 291 84.0 0.01190 244 100.2 0.00998 268 91.2 0.01096 292 83.7 0.01194 245 99.8 0.01002 269 90.9 0.01100 293 83.4 0.01198 246 99.4 0.01006 270 90.6 0.01104 294 83.2 0.01202 247 99.0 0.01010 271 90.2 0.01108 295 82.9 0.01207 248 98.6 0.01014 272 89.9 0.01112 296 82.6 0.01211 249 98.2 0.01018 273 89.6 0.01117 297 82.3 0.01215 250 97.8 0.01022 274 89.2 0.01121 298 82.0 0.01219 251 97.4 0.01027 275 88.9 0.01125 299 81.8 0.01223 252 97.0 0.01031 276 88.6 0.01129 300 81.5 0.01227

      a A. C. Fieldner, S. H. Katz, and S. P. Kinney, “Gas Masks for Gases Met in Fighting Fires,” U.S.

      Bureau of Mines, Technical Paper No. 248, 1921.

Part V Physical Agents

      Ionizing radiation may be defined as electromagnetic (X‐rays and gamma rays) and particulate radiation (alpha and beta particles, electrons, neutrons, and protons) with sufficient energy to disrupt an atom or a molecule. This is done by knocking out an electron, thereby “ionizing” the atom or molecule.

      Knowledge of radiation and safety problems associated with its use goes back more than 100 years, with the discovery of X‐rays in 1895 by Wilhelm Roentgen. On the same day that Roentgen announced his discovery, Emile Grubbe, a physicist working in Chicago with an apparatus similar to Roentgen's, developed severe skin burns after handling an energized cathode ray tube similar to the one used by Roentgen. This was the first work‐related injury from radiation. In 1896, Antoine Henri Becquerel discovered radioactivity while working with an ore called pitchblende. Investigation revealed three different radiations that originated in the ore. Ernest Rutherford named the first two radiations alpha and beta rays. P.V. Villard later named a third type of radiation, the gamma ray (later investigations showed that X‐rays and gamma rays were the same type of radiation). Alpha and beta particles are still occasionally referred to as alpha rays and beta rays as a result of this discovery.

      The discovery of these radiations opened new fields of scientific investigation and uses for these radiations. In parallel with the studies of the physics and chemistry of radioactive elements and the associated radiation, researchers were also examining the biomedical effects. With this expanded use of radiation, there were further reports of harmful effects, such as skin burns and hair loss when X‐rays were used in medical diagnosis. In 1899, the first case of a cancer, a basal cell carcinoma on a woman's face, was cured by X‐rays. In 1906, two French physiologists, Bergonie and Tribondeau, published their classical paper on the relative radiosensitivity of different cells and tissues. They found that the less differentiated a cell was, and the more frequently it divided, the more radiosensitive it was. Although to date we have found nothing to contradict their observations, much is understood now about the molecular biology basis for their findings. Since the time of their publication, an enormous amount of information on the nature of the interaction of radiation with living tissue and on the dose–effect and dose–response relationships has been amassed. Sources of information, such as the experiences of the radium dial painters, early radiologists, and uranium miners, showed that occupational overexposures led to harmful effects. Other major sources of information include populations that had been medically exposed to diagnostic and therapeutic radiation, survivors of the atomic bombings in Japan, data from radiation accidents, and epidemiological studies of populations exposed to low‐level radiation from nuclear facilities and from natural background. This body of knowledge forms the scientific basis for the radiation safety standards currently in use. After radiation safety guidelines were developed, occupational exposures that were within the radiation safety guidelines did not lead to harmful biomedical effects.

      2.1 Natural Radiation

      Cosmic radiation, when it enters the earth's atmosphere, consists mainly (90%) of high kinetic energy protons, with the remaining 10% being alpha particles, neutrons, and electrons. The interaction of these very high‐energy particles with the atmosphere leads to the production of certain radioactive isotopes (notably tritium (3H) and radiocarbon (14C)), muons (extremely high‐energy, heavy electrons