Mohamed N. Rahaman

Materials for Biomedical Engineering


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are the specific energies (energy per unit area) of the solid–vapor, solid–liquid, and liquid–vapor interfaces, respectively, and θ is the contact angle between the liquid and the solid (the angle between the tangent to the liquid–vapor interface at the contact point with the solid surface). At equilibrium, dG/dA = 0 and Eq. (5.2) gives

Schematic illustration of contributions to the Gibbs free energy change due to change in area dA of a liquid drop on a solid. Schematic illustration of wetting behavior between a liquid and a solid showing (a) good wetting, (b) poor wetting, and (c) complete wetting for a liquid of contact angle θ.

      As the physiological fluid is aqueous in nature, the extent to which water will wet a biomaterial and spread over it has significant consequences for its interaction with the aqueous medium in vivo. A material that shows good wetting and spreading by water (low θ ) is referred to as hydrophilic (literally, water‐loving). If the solid has a higher surface energy than water, there is a thermodynamic driving force for wetting and spreading of the liquid in order to reduce the energy of the system. In comparison, a material that shows poor wetting by water (high θ ) is referred to as hydrophobic (literally, water‐hating). In this case, the material has a lower surface energy than water and, thus, wetting is thermodynamically unfavorable because it will lead to an increase in the energy of the system.

      5.2.1 Determination of Surface Energy of Materials

      According to Eq. (5.3), the surface energy γsv is related to the surface energy of the liquid γlv, the solid–liquid interfacial energy γsl and the contact angle θ . Whereas γlv and θ can be easily measured, γsv and γsl cannot. Consequently, methods for estimating γsv often involve a combination of measuring γlv and θ, and estimating γsl using theoretical analyses, some of which can be fairly complex. While a variety of methods have been proposed, a useful method for polymers, based on its simplicity and accuracy, involves measuring θ for a single liquid of known surface energy (surface tension) γlv and using a theoretical expression for γsl (Girifalco and Good 1957):

      Example 5.1

      The measured contact angle of a water droplet on polymethyl methacrylate (PMMA) is 70°. Determine the surface energy of PMMA, given that the densities of PMMA and water are 1.2 and 1.0 g/cm3, respectively, and the surface tension of water is 73.0 mN/m.

      Solution:

      Another method applicable to materials of low surface energy, such as polymers, is referred to as the Zisman method. Fox and Zisman (1950, 1952) found that cos θ for a variety of polymers was approximately a monotonic function of γlv, that is

      (5.8)equation

Schematic illustration of Zisman plot for polymethyl methacrylate (PMMA) using various liquids.