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ADVANCES IN PHARMACEUTICAL TECHNOLOGY
A Wiley Book Series
Series Editors: Dennis Douroumis, University of Greenwich, UK Alfred Fahr, Friedrich–Schiller University of Jena, Germany Jurgen Siepmann, University of Lille, France Martin Snowden, University of Greenwich, UK Vladimir Torchilin, Northeastern University, USA
Titles in the Series
Hot‐Melt Extrusion: Pharmaceutical Applications Edited by Dionysios Douroumis
Drug Delivery Strategies for Poorly Water‐Soluble Drugs Edited by Dionysios Douroumis and Alfred Fahr
Computational Pharmaceutics: Application of Molecular Modeling in Drug Delivery Edited by Defang Ouyang and Sean C. Smith
Pulmonary Drug Delivery: Advances and Challenges Edited by Ali Nokhodchi and Gary P. Martin
Novel Delivery Systems for Transdermal and Intradermal Drug Delivery Edited by Ryan Donnelly and Raj Singh
Drug Delivery Systems for Tuberculosis Prevention and Treatment Edited by Anthony J. Hickey
Continuous Manufacturing of Pharmaceuticals Edited by Peter Kleinebudde, Johannes Khinast, and Jukka Rantanen
Pharmaceutical Quality by Design Edited by Walkiria S Schlindwein and Mark Gibson
In Vitro Drug Release Testing of Special Dosage Forms Edited by Nikoletta Fotaki and Sandra Klein
Characterization of Pharmaceutical Nano‐ and Microsystems Edited by Leena Peltonen
Biopharmaceutics: From Fundamentals to Industrial Practice Edited by Hannah Batchelor
Forthcoming Titles:
Process Analytics for Pharmaceuticals Edited by Jukka Rantanen, Clare Strachan and Thomas De Beer
Mucosal Drug Delivery Edited by Rene Holm
Biopharmaceutics
From Fundamentals to Industrial Practice
Edited by
HANNAH BATCHELOR
Strathclyde Institute of Pharmacy and Biomedical Sciences
University of Strathclyde Glasgow, United Kingdom
This edition first published 2022 © 2022 John Wiley & Sons Ltd
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Library of Congress Cataloging‐in‐Publication Data
Names: Batchelor, Hannah, editor.
Title: Biopharmaceutics : from fundamentals to industrial practice / edited by Hannah Batchelor.
Other titles: Biopharmaceutics (Batchelor) | Advances in pharmaceutical technology.
Description: First edition. | Chichester, UK ; Hoboken, NJ : John Wiley & Sons, 2022. | Series: Advances in pharmaceutical technology | Includes bibliographical references and index.
Identifiers: LCCN 2021050446 (print) | LCCN 2021050447 (ebook) | ISBN 9781119678281 (cloth) | ISBN 9781119678274 (adobe pdf) | ISBN 9781119678373 (epub)
Subjects: MESH: Biopharmaceutics–methods | Drug Design
Classification: LCC RM301.5 (print) | LCC RM301.5 (ebook) | NLM QV 35 | DDC 615.7–dc23/eng/20211101
LC record available at https://lccn.loc.gov/2021050446 LC ebook record available at https://lccn.loc.gov/2021050447
Cover Design: Wiley
Cover Image: © SCIEPRO/Getty Images
List of Contributors
Precious Akhuemokhan Institute of Pharmaceutical Sciences, King’s College London, London, United Kingdom
Abdul W. Basit Department of Pharmaceutics, UCL School of Pharmacy, University College London, London, United Kingdom
Hannah Batchelor Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom
Shanoo Budhdeo Seda Pharmaceutical Development Services, Alderley Edge,