coli with in...Scheme 7.13 Enantioselective thioesterification of racemic CPPA catalyzed by...Scheme 7.14 (a) Production of butylmalonyl‐CoA from (E)‐2‐hexenoyl‐CoA catal...Scheme 7.15 Biosynthesis of novel terminal‐alkyne‐bearing polyketide startin...Scheme 7.16 Pathways of JA biosynthesis in plant peroxisomes.Scheme 7.17 (a) Schematic pathway for the conversion of sucrose to triacylgl...Scheme 7.18 Acyl‐CoA‐dependent or –independent TAG synthesis pathway derived...Scheme 7.19 The de novo TAG biosynthesis pathway constructed by modification...Scheme 7.20 Condensation of glutamate and ammonia to generate glutamine cata...Scheme 7.21 Two primary pathways for glutamate synthesis in E. coli.Scheme 7.22 Biosynthetic pathway of nitrogen assimilation into glutamine, as...Scheme 7.23 Theanine production by coupling the reaction of GS with glucose ...Scheme 7.24 Biosynthesis of the antibiotic bacilysin from L-alanine and the ...Scheme 7.25 Hypothesized biosynthetic pathway from prephenate to bacilysin....Scheme 7.26 Enzymatic production of 2‐amino‐N‐(2‐furylmethyl)propanamide (AF...Scheme 7.27 ATP‐dependent formation of carbapenam‐3‐carboxylate catalyzed by...Scheme 7.28 Biosynthetic pathway of (5R)‐carbapen‐2‐em‐3‐carboxylic acid cat...Scheme 7.29 CarA catalyzed conversion of three different stereoisomers of 5‐...Scheme 7.30 Conversion of disubstituted‐5‐CMP derivatives into disubstituted...Scheme 7.31 Pyruvate carboxylase catalyzed MgATP‐dependent carboxylation of ...Scheme 7.32 Glucose metabolism in E. coli expressed with R. etli PYC. (a) Ae...Scheme 7.33 Central anaerobic metabolic pathway of mutant E. coli SBS110MG b...Scheme 7.34 Anaerobic mixed acid fermentation pathway for E. coli. (a) Coexp...Scheme 7.35 Predominant anaerobic metabolic pathways of C. glutamicum for su...Scheme 7.36 Metabolically engineered S. cerevisiae employed for succinate pr...Scheme 7.37 Major metabolic pathways for the production of malate in T. glab...Scheme 7.38 PMA biosynthesis based on comparative metabolome analysis.Scheme 7.39 Major metabolic pathways lead to the formation of fumarate I in Scheme 7.40 Proposed metabolic pathways of propionic acid fermentation with ...Scheme 7.41 Biosynthetic pathway toward 3‐hydroxypropionic acid from glucose...Scheme 7.42 Biosynthetic pathway of L-lysine via the d,L-diaminopimelate int...Scheme 7.43 Lysine and biotin production using PYC and biotin protein ligase...Scheme 7.44 Acetyl‐CoA carboxylase catalyzed carboxylation of acetyl‐CoA to ...Scheme 7.45 Type II fatty acid synthetic pathway. The ACC is a heterotetrame...Scheme 7.46 Fatty acid metabolic pathway of engineered E. coli. Overexpressi...Scheme 7.47 Engineered E. coli for free monounsaturated fatty acid productio...Scheme 7.48 Simplified principal metabolic pathways for lipid synthesis in Y...Scheme 7.49 Proposed mechanism of SCD‐mediated deregulation of fatty acid pa...Scheme 7.50 Lipid metabolism of engineered S. cerevisiae for fatty alcohol p...Scheme 7.51 Engineered E. coli for production of phloroglucinol from glucose...Scheme 7.52 Metabolically engineered S. argillaceus for production of mithra...Scheme 7.53 Metabolic pathways of engineered Y. lipolytica for TAAL synthesi...Scheme 7.54 Engineered ethanol‐driven biosynthetic system for production of ...Scheme 7.55 Biosynthesis of (2S)‐flavanones by engineered E. coli.Scheme 7.56 Engineering central metabolic pathways in E. coli for plant flav...Scheme 7.57 Engineered E. coli for biosynthesis of 7‐OMA starting from p‐cou...Scheme 7.58 Biosynthesis of 5‐deoxyflavanones in engineered E. coli.Scheme 7.59 Engineered E. coli for biosynthesis of 4‐hydroxycoumarin, naring...Scheme 7.60 Metabolically engineered S. cerevisiae for high kaempferol produ...Scheme 7.61 Modular strategy to optimize biosynthetic pathways in S. cerevis...Scheme 7.62 3‐Hydroxypropionic acid production from glucose through malonyl‐...Scheme 7.63 Proposed 3‐HP cycle of autotrophic CO2 fixation in the phototrop...Scheme 7.64 Biosynthetic pathway of 3‐HP in engineered Synechocystis.Scheme 7.65 Engineered S. elongatus with a balanced driving force module for...Scheme 7.66 3‐HP biosynthetic pathway in engineered S. cerevisiae. Bold arro...
8 Chapter 8Scheme 8.1 Merrifield’s solid‐phase synthesis of a dipeptide; Cbz, benzyloxy...Figure 8.1 Split–mix synthesis library in three cycles and each cycle with t...Scheme 8.2 Removal of the enzyme‐labile urethane protecting group from lipop...Scheme 8.3 Enzymatic cleavage of (a) endo‐ and (b) oxo‐linker to release pro...Figure 8.2 Orthogonality issues in biocatalysis.Scheme 8.4 Significance of orthogonality on the production of analogues usin...Scheme 8.5 Iterative synthesis of a 600‐member library from bergenin in two ...Scheme 8.6 Chemically synthesized combinatorial library of cross‐conjugated ...Scheme 8.7 Chemoenzymatically library synthesis by Ugi four‐component conden...Scheme 8.8 Unnatural oligosaccharide library synthesized by using UDP‐Gal an...Scheme 8.9 Enzymatic synthesis of the glycosylated amino acid derivative bui...Scheme 8.10 (a) Biosynthesis of Csypyrone B1 with mutant CsyB. (b) Combinato...Scheme 8.11 Chemical genetic strategy for discovery new macrolide antibiotic...Scheme 8.12 The precursor‐directed biosynthesis of micacocidin derivatives w...Scheme 8.13 DhbE catalyzed aryl acid activation and the generation of nonnat...Scheme 8.14 Triterpene saponin biosynthesis pathway in engineered yeast.Figure 8.3 Biodegradation pathway for propylene retrieved from the UM‐BBD. (...
Guide
4 Preface
8 Index
9 Wiley End User License Agreement
Pages
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2 iv
3 xi
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5 xiii
6 xv
7 1
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