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Library of Congress Cataloging‐in‐Publication Data
Names: You, Guofeng, editor. | Morris, Marilyn E., editor.
Title: Drug transporters : molecular characterization and role in drug disposition / edited by Guofeng You, Marilyn E. Morris.
Other titles: Drug transporters (2007)| Wiley series in drug discovery and development
Description: Third edition. | Hoboken, NJ : Wiley, [2022] | Series: Wiley series in drug discovery and development | Includes bibliographical references and index.
Identifiers: LCCN 2022000523 (print) | LCCN 2022000524 (ebook) | ISBN 9781119737551 (cloth) | ISBN 9781119739869 (adobe pdf) | ISBN 9781119739876 (epub)
Subjects: MESH: Biological Transport–physiology | Membrane Transport Proteins | Pharmacokinetics
Classification: LCC QH601(print) | LCC QH601(ebook) | NLM QU 120| DDC 571.6/4–dc23/eng/20220120
LC record available at https://lccn.loc.gov/2022000523 LC ebook record available at https://lccn.loc.gov/2022000524
Cover Design: Wiley
Cover Image: Courtesy of Lauren Aleksunes (Created in part with BioRender.com)
We would like to dedicate this book to our students, postdocs, and colleagues who have challenged and inspired us in our careers, and to our families William, Sarah, Jacqueline, and Kathleen Morris and Yifan and Peter Zhou who remain a continuing source of love and support in our lives.
LIST OF CONTRIBUTORS
Jeffry Adiwidjaja, Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
Lauren M. Aleksunes,Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA
Suresh V. Ambudkar,Laboratory of Cell Biology, Transport Biochemistry Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Ebehiremen N. Ayewoh,Department of Pharmaceutical Sciences, University of Maryland, Baltimore, MD, USA
Agnes Basseville,Bioinformatics Unit, Institut de Cancérologie de l'Ouest, Saint Herblain, France
Susan E. Bates,Division of Hematology/Oncology, Columbia University Medical Center, New York, NY, USA
Reina Bendayan,Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Rajinder K. Bhardwaj,Integrated Drug Development, Cetera Strategic Consulting, Parsippany, NJ, USA
Kim L. R. Brouwer,Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Dina Buitrago,Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA
Stephen M. Carl,Department Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, IN, USA; Discovery Pharmaceutics and Analytical Sciences, Bristol‐Myers Squibb Research Institute, Princeton, NJ, USA
Cindy H. Chau,Genitourinary Malignancies Branch, Molecular Pharmacology Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Eugene C. Chen,Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA, USA
Ayman El‐Kattan,DMPK, IFM Therapeutics, Boston, MA, USA
Osatohanmwen Jessica Enogieru,Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA; Pharmacokinetics and Drug Metabolism, Amgen Inc., South San Francisco, CA, USA
Melanie A. Felmlee,Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA, USA
William D. Figg,Genitourinary Malignancies Branch, Molecular Pharmacology Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Azusa Futatsugi,Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
Vadivel Ganapathy,Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX, USA
Kathleen M. Giacomini,Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA
Rajgopal Govindarajan,Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH, USA
Jeffry C. Granados,Department of Bioengineering, University of California, San Diego, CA, USA
Olafur Gudmundsson,Discovery Pharmaceutics and Analytical Sciences, Bristol‐Myers Squibb Research Institute, Princeton, NJ, USA
Matthew D. Harwood,Simcyp Division, Certara UK Ltd., Sheffield, UK
Dea Herrera‐Ruiz,Facultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, México
Robert S. Jones,Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA, USA
Melanie S. Joy,Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA
Yukio Kato,Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
Richard B. Kim,Departments of Medicine, Physiology & Pharmacology and Oncology, The University of Western Ontario, London, Ontario, Canada
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