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DNA Origami


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      Table of Contents

      1  Cover

      2  Title Page

      3  Copyright Page

      4  List of Contributors

      5  Preface

      6  1 DNA Origami Technology: 1.1 Introduction 1.2 Two‐Dimensional DNA Origami 1.3 Programmed Arrangement of Multiple DNA Origami Components 1.4 Three‐Dimensional DNA Origami Structures 1.5 Modification and Functionalization of 2D DNA Origami Structures 1.6 Single‐Molecule Detection and Sensing using DNA Origami Structures 1.7 Application to Single Biomolecule AFM Imaging 1.8 Single‐Molecule Fluorescence Studies 1.9 DNA Molecular Machines 1.10 Selective Incorporation of Nanomaterials and the Applications 1.11 Dynamic DNA Origami Structures Responsive to External Stimuli 1.12 Conjugation of DNA Origami to Lipid 1.13 DNA Origami for Biological Applications 1.14 Conclusions References

      7  2 Wireframe DNA Origami and Its Application as Tools for Molecular Force Generation 2.1 Introduction 2.2 Pre‐Origami Wireframe DNA Nanostructures 2.3 Hierarchical DNA Origami Wireframe 2.4 Entire DNA Origami Design 2.5 DNA Origami Wireframe as Tools for Molecular Force Application 2.6 Conclusions References

      8  3 Capturing Structural Switching and Self‐Assembly Events Using High‐Speed Atomic Force Microscopy 3.1 Introduction 3.2 DNA Origami Nanomachines 3.3 Ion‐Responsive Mechanical DNA Origami Devices 3.4 Photoresponsive Devices 3.5 Two‐Dimensional Self‐Assembly Processes 3.6 Sequential Self‐Assembly 3.7 Photostimulated Assembly and Disassembly 3.8 Conclusions and Perspectives References

      9  4 Advancement of Computer‐Aided Design Software and Simulation Tools for Nucleic Acid Nanostructures and DNA Origami 4.1 Introduction 4.2 General‐Purpose Software 4.3 Software for Designing Small DNA Nanostructures 4.4 Software for Designing DNA Origami 4.5 Software for Designing RNA Nanostructures 4.6 Software for Designing Base Sequence 4.7 Software for Simulating Nucleic Acid Nanostructures 4.8 Summary and Future Perspective References

      10  5 Dynamic and Mechanical Applications of DNA Nanostructures in Biophysics 5.1 Introduction 5.2 Applications 5.3 Tools for Quantifying DNA Devices and their Functions 5.4 Modeling and Analysis 5.5 Conclusion References

      11  6 Plasmonic Nanostructures Assembled by DNA Origami 6.1 Introduction 6.2 Optical Properties of the DNA Origami‐Based Plasmonic Nanostructures 6.3 Nanoparticle Functionalization with DNA 6.4 DNA Origami‐Based Plasmonic Assemblies 6.5 Surface‐Enhanced Raman Scattering (SERS) and Other Plasmonic Effects 6.6 Conclusion Acknowledgments References

      12  7 Assembly of Nanoparticle Superlattices Using DNA Origamias a Template