determination to trace the DNA-complex that was responsible for the Innsmouth syndrome, in order to enable me to prove to her that she wasn’t afflicted, and that her dreams were only dreams. In fact, it didn’t; I was hurt by her rejection, and depressed. I continued to work as hard as I ever had, but I found it increasingly difficult to go to Innsmouth, to stay in the hotel where she lived, and to walk through the streets which she owned.
I began to look for someone else to soothe my emotional bruises, while Ann and I drifted steadily apart. We were no longer good friends in any real sense, though we kept up some kind of a pretense whenever we met.
In the meantime, the members of my experimental sample continued to die. I lost three more in the second year, and it became even more obvious that whatever I discovered wasn’t going to be of any practical import to the people whose DNA I was looking at. In a way, it didn’t matter that much to the program—the DNA that Gideon and all the rest had provided still existed, carefully frozen and stored away. The project was still healthy, still making headway.
In the third year, I finally found what I was looking for: an inversion on the seventh chromosome, which had trapped seven genes, including three oddballs. In homozygotes like Gideon, the genes paired up and were expressed in the normal way; in heterozygotes, like most of my sample—including all of the survivors—the chromosomes could only pair up if one of them became looped around, stopping several of the genes from functioning. I didn’t know what all of the genes did, or how—but my biochemical analyses had given me a partial answer.
I drove to Innsmouth the next day, in order to tell Ann the news. Although our relationship had soured and fallen apart, I still owed her as much of an explanation as I could now give.
“Do you know what Haeckel’s law is?” I asked her, while we walked beside the Manuxet, past the place where the Marsh refinery had once been located.
“Sure,” she said. “I read up on the whole thing, you know, after we got involved. Haeckel’s law says that ontogeny recapitulates phylogeny—that the embryo, in developing, goes through a series of stages which preserve a kind of memory of the evolutionary history of an organism. It’s been discredited, except as a very loose metaphor. I always thought that the Innsmouth look might turn out to have something to do with the fact that the human embryo goes through a stage where it develops gills.”
“Only the ghosts of gills,” I told her. “You see, the same embryonic structures that produce gills in fish produce different structures in other organisms; it’s called homology. Conventional thinking, muddied by the fact that we don’t really understand the business of blueprinting for physical structure, supposes that when natural selection works to alter a structure into its homologue—as when the fins of certain fish were modified by degrees into the legs of amphibians, for instance, or the forelimbs of certain lizards became the wings of birds—the blueprint genes for the new structure replace the blueprint genes for the old. But that’s not the only way it could happen. It may be that the new genes arise at different loci from the old ones, and that the old ones are simply switched off. Because they aren’t expressed any more in mature organisms they’re no longer subject to eliminative natural selection, so they aren’t lost, and even though they’re bound to be corrupted by the accumulation of random mutations—which similarly aren’t subject to elimination by natural selection—they remain within the bodies of descendant species for millions of years. If so, they may sometimes be expressed, if there’s a genetic accident of some kind that prevents their being switched off in a particular organism.”
She thought about it for a few moments, and then she said: “What you’re saying is that human beings—and, for that matter, all mammals, reptiles and amphibians—may be carrying around some of the blueprint genes for making fish. These are normally dormant—untroublesome passengers in the body—but under certain circumstances, the switching mechanism fails and they begin to make the body they’re in fishy.”
“That’s right,” I said. “And that’s what I shall propose as the cause of the Innsmouth syndrome. Sometimes, as with Gideon, it can happen very early in life, even before birth. In other instances it’s delayed until maturity, perhaps because the incipient mutations are suppressed by the immune system, until the time when ageing sets in and the system begins to weaken.”
I had to wait a little while for her next question, though I knew what it would be.
“Where do the dreams fit in?” she asked.
“They don’t,” I told her. “Not into the biology. I never really thought they did. They’re a psychological thing. There’s no psychotropic protein involved here. What we’re talking about is a slight failure of the switching mechanism that determines physical structure. Ann, the nightmares come from the same place as the Esoteric Order of Dagon and Zadok Allen’s fantasies—they’re a response to fear, anxiety and shame. They’re infectious in exactly the same way that rumors are infectious—people hear them, and reproduce them. People who have the look know that the dreams come with it, and knowing it is sufficient to make sure that they do. That’s why they can’t describe them properly. Even people who don’t have the look, but fear that they might develop it, or feel that for some eccentric reason they ought to have it, can give themselves nightmares.”
She read the criticism in my words, which said that I had always been right and she had always been wrong, and that she had had no good cause for rejecting my proposal. “You’re saying that my dreams are purely imaginary?” she said, resentfully. People always are resentful about such things, even when the news is good, and despite the fact that it isn’t their fault at all.
“You don’t have the inversion, Ann. That’s quite certain now that I’ve found the genes and checked out all the sample traces. You’re not even heterozygous. There’s no possibility of your ever developing the look, and there’s no reason at all why you have to avoid getting married.”
She looked me in the eye, as disconcertingly as Gideon Sargent ever had, though her eyes were perfectly normal, and as grey as the sea.
“You’ve never seen a shoggoth,” she said, in a tone profound with despair. “I have—even though I don’t have the words to describe it.”
She didn’t ask me whether I was renewing my proposal— maybe because she already knew the answer, or maybe because she hadn’t changed her own mind at all. We walked on for a bit, beside that dull and sluggish river, looking at the derelict landscape. It was like the set for some schlocky horror movie.
“Ann,” I said, eventually, “you do believe me, don’t you? There really isn’t a psychotropic element in the Innsmouth syndrome.”
“Yes,” she said. “I believe you.”
“Because,” I went on, “I don’t like to see you wasting your life away in a place like this. I don’t like to think of you, lonely in selfimposed exile, like those poor lookers who shut themselves away because they couldn’t face the world—or who were locked up by mothers and fathers or brothers and sisters or sons and daughters who couldn’t understand what was wrong, and whose heads were filled with stories of Obed Marsh’s dealings with the devil and the mysteries of Dagon.
“That’s the real nightmare, don’t you see—not the horrid dreams and the daft rites conducted in the old Masonic Hall, but all the lives that have been ruined by superstition and terror and shame. Don’t be part of that nightmare, Ann; whatever you do, don’t give in to that. Gideon Sargent didn’t give in—and he told me once, although I didn’t quite understand what he meant at the time, that it was up to me to make sure that you wouldn’t, either.”
“But they got him in the end, didn’t they?” she said. “The Deep Ones got him in the end.”
“He was killed in an accident at sea,” I told her, sternly. “You know that. Please don’t melodramatize, when you know you don’t believe it. You must understand, Ann—the real horrors aren’t in your dreams, they’re in what you might let your dreams do to you.”
“I know,” she said,