Surya K. De

Applied Organic Chemistry


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Ms. Katherine Wong, as well as their staffs Ms. Pinky Sathishkumar, Ms. Abisheka Santhoshini who helped me to complete this book.

      Finally, I wish to thank my family members for their continual understanding and support.

      I welcome and, in fact, earnestly request readers to notify me of any suggestions for improving this book.

       Surya K. De

      San Diego, CA, USA

      March 2020

      This book is unique in that it covers most reactions that are the syllabus of undergrascapduate and postgraduate students. The reaction mechanisms are shown in details with step‐by‐step explanation of the processes. Most of the reactions' applications and experimental procedures are also given. Professional researcher may utilize it as a handbook due to its references to original literature, recent reviews, and application of named reactions and reagents frequently used in organic synthesis.

      Surya K. De received his BS degree from Midnapore College and his PhD degree from Jadavpur University. His first book, Cancer & You: What Everyone Needs to Know About Cancer and Its Prevention, was published in 2018. He has published over 100 peer‐reviewed papers in reputed international journals, covering a broad array of specialized topics in science, and he holds 15 US patents for his inventions. Due to Dr. De's abundant research contributions in the areas of cancer, metabolic diseases, organic and medicinal chemistry, and neuroscience, he earned the distinction of Fellow of the Royal Society of Chemistry (London, UK) in 2010; he was subsequently awarded the status of Chartered Chemist in 2011. Furthermore, he is an elected alternate councilor in the American Chemical Society (San Diego section). Dr. De resides in San Diego, California, where he loves the scenic coastline and sunny skies.

      The author would like to extend his gratitude to the original publishers for experimental procedures for granting permission to use in this book. The publishers include the American Chemical Society, Elsevier, the Royal Society of Chemistry, John Wiley & Sons, Wiley VCH‐Verlag, Thieme, and the Japan Institute of Heterocyclic Chemistry. I would like to thank all inventors for patent literatures cited in this book.

Abbreviation Name Chemical structure
Ångström NA
Ac Acetyl image
Acac Acetylacetonyl image
AIBN 2,2′‐Azobisisobutyronitrile image
Alloc Allyloxycarbonyl image
Aq Aqueous With water
Ar Aryl Substituted aromatic ring
9‐BBN 9‐Borabicyclo[3.3.1]nonane image
BINAL‐H 2,2′‐Dihydroxy‐1,1′‐binaphthyl lithium aluminum hydride image
BINAP 2,2′‐Bis(diphenylphosphino)‐1,1′‐binaphthyl image
BINOL 1,1′‐Bi‐2,2′‐naphthol image
BMS Borane dimethyl sulfide complex H3B • SMe2
Name Chemical structure
Boc tert‐Butoxycarbonyl image
BOM Benzyloxymethyl image
b.p. Boiling point NA
BPO Benzoyl peroxide image
Bn Benzyl image
br Broad NA
Bz Benzoyl image
n‐Bu n‐Butyl image
t‐Bu tert‐Butyl image
°C Degree Celsius