Table of Contents 1
COVER
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INTRODUCTION: THE POWER OF PRECISION HEALTH
THE PRECISION HEALTH PAST—AND PRESENT
KEY PRINCIPLES OF PRECISION HEALTH
THE TIME IS RIGHT FOR PRECISION HEALTH
ABOUT ME
THE ORIGINS OF PRECISION HEALTH AT STANFORD
ABOUT THE BOOK
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CHAPTER 1: THE STATE OF U.S. HEALTH AND HEALTH CARE DELIVERY
THE HEALTH PARADOX
THE U.S. HEALTH CARE CONUNDRUM
THE “SOPHISTICATED” TECHNOLOGY IN DOCTORS’ OFFICES
THE UNFULFILLED POTENTIAL OF ELECTRONIC HEALTH RECORDS
WHAT HANDICAPS THE U.S. HEALTH CARE SYSTEM
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CHAPTER 2: THERE’S MORE TO “HEALTH” THAN HEALTH CARE
PRECISION HEALTH AND POPULATION HEALTH
GENES ARE ONE PIECE OF THE HEALTH PUZZLE
BEHAVIORS CAN CHANGE—AND DO CHANGE
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CHAPTER 3: THE INNOVATION AND DISRUPTION POWERING PROGRESS IN HEALTH
COMMERCIALIZATION OF SCIENTIFIC AND TECHNOLOGICAL ADVANCES AND THE RELATIONSHIP BETWEEN ACADEMIA AND INDUSTRY
HOW DIGITAL HEALTH CAN DRIVE DISRUPTION AND INNOVATION
THE ENVIRONMENTS THAT FOSTER INNOVATION
HOW THE ARTS HELPED ADVANCE ANTIMICROBIAL THERAPY
SHATTERING THE STROKE TREATMENT STOPWATCH
DEVELOPING THE THERAPEUTIC OPPORTUNITIES ASSOCIATED WITH STEM CELLS AND REGENERATIVE MEDICINE
BRINGING INNOVATION TO IMMUNOLOGY
THE APPROACHING REVOLUTION IN SLEEP RESEARCH
THE PROGRESS UNDERWAY IN PREDICTING, PREVENTING, AND CURING ALLERGIES
THE PROGRESS TOWARD PREDICTING, PREVENTING, AND CURING MENTAL ILLNESS
ADVANCING EARLY DETECTION AND TREATMENT OF AUTISM
THE BENEFIT OF BIG SCIENCE / BIG PHARMA COOPERATION
MAKING BABIES WITH MODERN TECHNOLOGY
ADVANCING SCIENCE THROUGH CITIZEN SCIENTISTS
DEVELOPING NEW THERAPEUTICS AND REPURPOSING EXISTING DRUGS
ACCELERATING INNOVATION IN HEALTH TECHNOLOGY
HOW DATA CAN IMPROVE MEDICAL EDUCATION AND HELP MEASURE PHYSICIAN PERFORMANCE
DEVELOPING NEW AND BETTER DIAGNOSTIC TOOLS
LEVERAGING INTERDISCIPLINARY INNOVATION TO ADVANCE GLOBAL HEALTH
BRINGING TRANSPARENCY TO DRUG PRICING
DOING THE “IMPOSSIBLE”: USING PLANTS TO PRODUCE “MEAT”
MINIMIZING MISTAKES IN MEDICAL RESEARCH
INNOVATION GONE WRONG: THOUGHTS ON THERANOS
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CHAPTER 4: FUNDAMENTAL, DISCOVERY‐FOCUSED RESEARCH: THE FOUNDATION OF BIOMEDICAL BREAKTHROUGHS
THE MANY DIFFERENT REASONS FOR RESEARCH
A BREAKTHROUGH ENABLED BY BASIC SCIENCE
MEDICAL RESEARCH AND UNEXPECTED DISCOVERIES
DISCOVERIES IN MOLECULAR BIOLOGY THAT ENABLED GENES TO BE CLONED
THE BIRTH OF BIOTECHNOLOGY: CLONING GENES TO PRODUCE PROTEIN
DISCOVERY OF A NOVEL MECHANISM RESPONSIBLE FOR REGULATION OF GENE EXPRESSION
ELUCIDATION OF THE STRUCTURE OF COMPLEX PROTEINS
FOUNDING THE FIELD OF COMPUTATIONAL STRUCTURAL BIOLOGY
UNRAVELING HOW NEURONS COMMUNICATE WITH ONE ANOTHER
ILLUMINATING OUR UNDERSTANDING OF THE BRAIN
PUSHING PHYSICS—AND OTHER DISCIPLINES—TO NEW FRONTIERS
EXPANDING OUR UNDERSTANDING OF THE BRAIN’S DEVELOPMENT—AND COUNTERING ITS DECLINE
UNDERSTANDING THE MYSTERIES OF AGING
REVEALING THE ROOTS OF REGENERATION
BREAKTHROUGH TECHNOLOGIES AS A CATALYST FOR BIOMEDICAL DISCOVERIES
A TOOL PROVIDING NEW INSIGHTS ABOUT BIOLOGICAL SPECIMENS
TRAINING THE NEXT GENERATION OF LEADERS IN BIOMEDICINE