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Table of Contents
1 Cover
2 DNA- and RNA-Based Computing Systems
5 1 DNA Computing: Origination, Motivation, and Goals – Illustrated Introduction 1.1 Motivation and Applications 1.2 DNA‐ and RNA‐Based Biocomputing Systems in Progress 1.3 DNA‐Based Information Storage Systems 1.4 Short Conclusions and Comments on the Book References
6 2 DNA Computing: Methodologies and Challenges 2.1 Introduction to DNA Computing Methodologies 2.2 Key Developments in DNA Computing 2.3 Challenges Acknowledgment References
7 3 DNA Computing and Circuits 3.1 From Theory to DNA Implementations 3.2 Application‐Specific DNA Circuits Acknowledgments References
8 4 Connecting DNA Logic Gates in Computational Circuits 4.1 DNA Logic Gates in the Context of Molecular Computation 4.2 Connecting Deoxyribozyme Logic Gates 4.3 Connecting Gates Based on DNA Strand Displacement 4.4 Logic Gates Connected Via DNA Four‐Way Junction (4WJ) 4.5 Conclusion References Note
9 5 Development of Logic Gate Nanodevices from Fluorogenic RNA Aptamers 5.1 Nucleic Acid: The Material of Choice for Nanotechnology 5.2 RNA Aptamers are Modular and Programmable Biosensing Units 5.3 Construction of RNA Nanoparticles with Integrated Logic Gate Operations Using Light‐Up Aptamers 5.4 Conclusion Acknowledgments References
10 6 Programming Molecular Circuitry and Intracellular Computing with Framework Nucleic Acids 6.1 Framework Nucleic Acids 6.2 A Toolbox for Biomolecular Engineering of Living Systems 6.3 Targeted Applications 6.4 Nucleic Acid Nanotechnology‐Enabled Computing Kernel 6.5 I/O and Human–Computer Interfacing 6.6 Information Storage 6.7 Perspectives 6.8 Conclusion References
11 7 Engineering DNA Switches for DNA Computing Applications 7.1 Introduction 7.2 Selecting Recognition Element Based on Input 7.3 Engineering Switching Mechanisms 7.4 Engineering Logic Output Function Response 7.5 Optimizing Switch Response 7.6 Perspective Acknowledgments References
12 8 Fluorescent Signal Design in DNA Logic Circuits 8.1 Basic Signal Generation Strategies Based on DNA Structures 8.2 Designs for Constructing Multi‐output Signals 8.3 Summary and Outlook References
13 9 Nontraditional Luminescent and Quenching Materials for Nucleic Acid‐Based Molecular Photonic Logic 9.1 Introduction 9.2 DNA Molecular Photonic Logic Gates 9.3 Nontraditional Luminescent Materials 9.4 Semiconductor “Quantum Dot” Nanocrystals 9.5 Lanthanide‐Based Materials