Plateletpheresis 6.3 Erythrocytapheresis 6.4 Leukapheresis for the collection of granulocytes 6.5 Leukapheresis for the collection of mononuclear cells 6.6 Leukapheresis for the collection of peripheral blood stem cells 6.7 Donor selection and complications of cytapheresis in normal donors 6.8 Plasmapheresis and source plasma References
12 7 Laboratory Testing of Donated Blood 7.1 Background 7.2 Safety of the blood supply 7.3 Blood component testing 7.4 Testing for transmissible diseases 7.5 Other laboratory testing 7.6 Summary References
13 8 Blood Groups 8.1 Red blood cell antigens and groups 8.2 ABO system 8.3 The Rh system 8.4 Other red cell blood groups 8.5 Antibodies to red cell antigens 8.6 Function of molecules containing red cell antigens 8.7 Platelets 8.8 Granulocytes References
14 9 Laboratory Detection of Blood Groups and Provision of Red Cells 9.1 Immunologic mechanisms of red cell destruction 9.2 Methods of detecting red cell antibody–antigen reactions 9.3 The antiglobulin test 9.4 Red cell compatibility testing 9.5 Red cell antibody identification 9.6 Strategies for making red cells available for transfusion 9.7 Approach to the patient with an incompatible crossmatch 9.8 Hemolytic disease of the fetus and newborn 9.9 Platelet compatibility 9.10 Granulocyte compatibility References
15 10 Clinical Uses of Blood Components 10.1 Blood component therapy 10.2 Transfusion of components that contain red blood cells 10.3 Transfusion of components and derivatives that contain coagulation factors 10.4 Transfusion of platelets 10.5 Granulocyte transfusion 10.6 Cytomegalovirus‐safe blood components 10.7 Graft‐versus‐host disease References
16 11 Transfusion Therapy in Specific Clinical Situations 11.1 Acute blood loss and trauma 11.2 Cardiovascular surgery 11.3 Hematopoietic cell transplantation 11.4 Solid organ transplantation 11.5 Transfusion of patients with paroxysmal nocturnal hemoglobinuria 11.6 Neonates 11.7 Pediatric patients 11.8 Transfusion therapy in hemoglobinopathies 11.9 Hemophilia and von Willebrand disease 11.10 Autoimmune hemolytic anemia 11.11 Pregnant women 11.12 Acquired immune deficiency syndrome 11.13 Transfusing patients with IgA deficiency 11.14 Autoimmune thrombocytopenia 11.15 Neonatal alloimmune thrombocytopenia 11.16 Neonatal alloimmune neutropenia 11.17 Autoimmune neutropenia 11.18 Rare blood types References
17 12 Patient Blood Management 12.1 Evidence‐based guidelines for transfusion 12.2 Physician and health professional education program 12.3 Mechanism to monitor blood use and adherence to guidelines 12.4 Preoperative Anemia