Table of Contents 1
Cover
4
Preface
5
1 History for Canonical and Non-canonical Structures of Nucleic Acids
1.1 Introduction
1.2 History of Duplex
1.3 Non-Watson–Crick Base Pair
1.4 Nucleic Acid Structures Including Non-Watson–Crick Base Pairs
1.5 Perspective of the Research for Non-canonical Nucleic Acid Structures
1.6 Conclusion and Perspective
References
6
2 Structures of Nucleic Acids Now
2.1 Introduction
2.2 Unusual Base Pairs in a Duplex
2.3 Non-canonical Backbone Shapes in DNA Duplex
2.4 Branched DNA with Junction
2.5 Multi-stranded DNA Helices
2.6 Structures in RNA
2.7 Conclusion
References
7
3 Stability of Non-canonical Nucleic Acids
3.1 Introduction
3.2 Factors Influencing Stabilities of the Canonical Duplexes
3.3 Thermodynamic Analysis for the Formation of Duplex
3.4 Factors Influencing Stabilities of the Non-canonical Nucleic Acids
3.5 Thermodynamic Analysis for the Non-canonical Nucleic Acids
3.6 Conclusion
References
8
4 Physicochemical Properties of Non-canonical Nucleic Acids
4.1 Introduction
4.2 Spectroscopic Properties of Non-canonical Nucleic Acids
4.3 Chemical Interactions on Non-canonical Nucleic Acids
4.4 Chemical Platform on the Non-canonical Structures
4.5 Physicochemical Property of Non-canonical Nucleic Acids in Cell
4.6 Conclusion
References
9
5 Telomere
5.1 Introduction
5.2 Structural Properties of Telomere
5.3 Biological Relevance of Telomere G4
5.4 Other Non-canonical Structures Related to Telomere Region
5.5 Conclusion
References
10
6 Transcription
6.1 Introduction
6.2 Transcription Process
6.3 Transcription Process Perturbed by Certain Sequences of DNA and RNA
6.4 Transcription Process Perturbed by Non-canonical Structures of DNA and RNA
6.5 Conclusion
References
11
7 Translation
7.1 Introduction
7.2 RNAs Involved in Translation Machinery
7.3 General Process of Translation
7.4 RNA Structures Affecting Translation Reaction
7.5 Conclusion
References
12
8 Replication
8.1 Introduction
8.2 Replication Machineries
8.3 Replication Initiation
8.4 DNA Strand Elongation
8.5 Termination of Replication
8.6 Chemistry of the Replication and Its Regulation
8.7 Conclusion
References
13
9 Helicase
9.1 Introduction
9.2 Function and Structure of Helicases
9.3 Unwinding of Non-canonical
