Группа авторов

Digital Transformation of the Laboratory


Скачать книгу

the LotF, whether it is the “raw” data coming off the instruments or the “refined” result data derived from the raw data, will continue to be key to the LotF; if anything, the criticality and value of the digital assets generated by LotFs will become even more important in the future. Data‐focused technologies and standards such as IoT, FAIR, SiLA, and Allotrope will ensure that the high‐value digital assets are well managed and secured. The increasing focus on data privacy, security, and protection will put heavy pressure on LotFs with regard to good governance and compliance.

      1 1 Deloitte Tackling digital transformation. (2019). https://www2.deloitte.com/us/en/insights/industry/life-sciences/biopharma-company-of-the-future.html (accessed 1 February 2020).

      2 2 Shandler, M. (2018). Life science's lab informatics digital criteria to separate vendor leaders from laggards. Gartner G00336151. https://www.gartner.com/en/documents/3895920/life-science-s-lab-informatics-digital-criteria-to-separ (accessed 1 February 2020).

      3 3 Open Science Massively Open Online Community (MOOC) https://opensciencemooc.eu/ (accessed 1 February 2020).

      4 4 Vidyasagar, A. (2018). What is CRISPR? https://www.livescience.com/58790-crispr-explained.html (accessed 1 February 2020).

      5 5 Open Science https://openscience.com/ (accessed 1 February 2020).

      6 6 Tapscott, D. and Tapscott, A. (2016). Blockchain Revolution. New York. ISBN: 978‐0‐241‐23785‐4: Penguin Random House.

      7 7 Shute, R.E. (2017). Blockchain technology in drug discovery: use cases in R&D. Drug Discovery World 18 (October Issue): 52–57. https://www.ddw-online.com/informatics/p320746-blockchain-technology-in-drug-discovery:-use-cases-in-r&d.html.

      8 8 Gawas, A.U. (2015). An overview on evolution of mobile wireless communication networks: 1G‐6G. International Journal on Recent and Innovation Trends in Computing and Communication 3: 3130–3133. http://www.ijritcc.org.

      9 9 Chovan, T. and Guttman, A. (2002). Microfabricated devices in biotechnology and biochemical processing. Trends in Biotechnology 20 (3): 116–122. https://doi.org/10.1016/s0167-7799(02)01905-4.

      10 10 Zimmerman, J.B., Anastas, P.T., Erythropel, H.C., and Leitner, W. (2020). Designing for a green chemistry future. Science 367 (6476): 397–400. https://doi.org/10.1126/science.aay3060.

      11 11 (i) Notman, N. (2018). Seeing drugs in 3D. Chemistry World (April Issue) https://www.chemistryworld.com/features (accessed 1 February 2020). (ii) Chapman, K. (2020). 3D printing the future. Chemistry World (February Issue). https://www.chemistryworld.com/features/3d-printing-in-pharma/3008804.article (accessed 1 February 2020).

      12 12 23andMe https://www.23andme.com/ (accessed 1 February 2020).

      13 13 Ancestry https://www.ancestry.com/ (accessed 1 February 2020).

      14 14 Plowright, A., Johnstone, C., Kihlberg, J. et al. (2011). Hypothesis driven drug design: improving quality and effectiveness of the design‐make‐test‐analyse cycle. Drug Discovery Today 17: 56–62. https://doi.org/10.1016/j.drudis.2011.09.012.

      15 15 Tawfik, M., Salzmann, C., Gillet, D., et al. (2014). Laboratory as a service (LaaS): a model for developing and implementing remote laboratories as modular components. 11th International Conference on Remote Engineering and Virtual Instrumentation. IEEE. https://doi.org/10.1109/REV.2014.6784238.

      16 16 Data Center Container (2019). https://www.techopedia.com/definition/2104/data-center-container (accessed 1 February 2020).

      17 17 Francis Crick Institute https://www.crick.ac.uk/about-us/our-vision (accessed 1 February 2020).

      18 18 Hok Architects Francis crick lab design. https://www.hok.com/projects/view/the-francis-crick-institute/ (accessed 1 February 2020).

      19 19 Crow, J.M. (2020). Sustainable lab buildings. Chemistry World 17 (3): 24–29.

      20 20 Steele, J. (2019). https://www.forbes.com/sites/jeffsteele/2019/08/12/the-future-of-life-science-and-tech-innovation-is-in-clusters/ (accessed 1 February 2020).

      21 21 Economist The world's most valuable resource is no longer oil but data (2017). https://www.economist.com/leaders/2017/05/06/the-worlds-most-valuable-resource-is-no-longer-oil-but-data