2.64. Axial contrast‐enhanced CT demonstrating an ill‐defined mass diagnosed as a mucoepidermoid carcinoma (arrow).
Figure 2.65. Axial contrast‐enhanced CT demonstrating large bulky cervical lymphadenopathy with ill‐defined borders, diagnosed as a mucoepidermoid carcinoma.
Figure 2.66. Reformatted coronal contrast‐enhanced CT demonstrating an ill‐defined heterogeneous density mass diagnosed as a mucoepidermoid carcinoma (arrow).
Figure 2.67. Coronal contrast‐enhanced MRI of the skull base demonstrating a mass extending through the skull base via the left foramen ovale (arrow), diagnosed as an adenoid cystic carcinoma originating from a minor salivary gland of the pharyngeal mucosa.
Figure 2.68. Axial CT in bone window demonstrating a mass eroding through the left side of the hard palate and extending into the maxillary sinus (arrow) diagnosed as adenoid cystic carcinoma.
Figure 2.69. Coronal CT corresponding to the case illustrated in Figure 2.68 with a mass eroding the hard palate and extending into the left maxillary sinus (arrow).
NEOPLASMS – NON‐SALIVARY
Benign
Lipoma
In the cervical soft tissues, lipomas are slightly more commonly seen within the parotid gland rather than periparotid. Lipomas of the salivary glands are uncommon (Shah 2002). The CT and MRI characteristics are those of subcutaneous fat with CT density very low (approximately 100 H) and hyperintense on both T1 and T2. Lipomas tend to be echogenic on US. They may be uniform on imaging but may have areas of fibrosis. The heterogenous density from fibrosis, or hemorrhage, carries the additional differential diagnosis of liposarcoma or other neoplasms (Som et al. 1995), (Figures 2.72 and 2.73).
Figure 2.70. Reformatted contrast‐enhanced coronal CT with a mass in the right submandibular gland (arrow) diagnosed as an adenoid cystic carcinoma.
Figure 2.71. Reformatted sagittal contrast‐enhanced CT corresponding to the case illustrated in Figure 2.65.
Figure 2.72. Axial contrasted‐enhanced CT of the head with a fat density mass at the level of the parotid gland and extending to the submandibular gland, diagnosed as a lipoma.
Figure 2.73. Axial contrast‐enhanced CT through the submandibular gland with fat density mass partially surrounding the gland. A lipoma was diagnosed.
Neurogenic tumors
Neurogenic tumors are uncommon in the salivary glands but when encountered are most commonly found in the parotid gland. Most facial nerve schwannomas are on the intratemporal facial nerve with only 9% extra‐temporal and in the parotid gland (Shimizu et al. 2005), (Figures 2.74 through 2.76 ). These are difficult to preoperatively diagnose as they do not typically present with facial nerve dysfunction. As seen in other parts of the body, they tend to be sharply marginated and have an ovoid shape along the axis of the involved nerve, such as the facial nerve. The CT density is that of soft tissue but post‐contrast, both enhance (schwannoma slightly greater than neurofibroma). Both are noted as low signal on T1 and high on T2. MRI enhancement pattern follows that of CT. They may demonstrate a target sign appearance with peripheral hyperintensity relative to a central hypointensity (Martin et al. 1992; Suh et al. 1992; Shimizu et al. 2005). However, this sign is not pathognomonic and may be seen in schwannomas or neurofibromas. Increased uptake is seen on FDG PET in both diseases. The neurofibroma may be associated with Von Recklinghausen's disease. Although, most schwannomas and neurofibromas are benign, they are reported as demonstrating increased uptake (hypermetabolism of glucose) of 18F‐FDG on PET imaging (Hsu et al. 2003). Although the calculated standard uptake value (SUV) can be helpful in differentiating benign from malignant lesions, there is a significant overlap (Ioannidis and Lau 2003). There is difficulty in separating low‐grade malignant lesions from benign lesions (Ioannidis and Lau 2003), (Figures 2.77 and 2.78). Plexiform neurofibromas are also slow‐growing and rare. They present with multiple cord‐like masses and are far more common in the parotid gland relative to other salivary glands. By CT and MRI, they are sometimes described as a “branching” pattern or “bag of worms” secondary to the multiple lesions growing along nerve branches. They have CT and MRI signal characteristics like neurofibromas and schwannomas including the “target sign” (Lin and Martel 2001; Aribandi et al. 2006). The target sign may