Группа авторов

Clinical Obesity in Adults and Children


Скачать книгу

Global Institute’s economic analysis of the social burdens generated by human beings. Obesity is one of the top three social burdens.

      (Source: Reproduced from Dobbs et al. [79].)

      Thinking about the economics of obesity is valuable as it alters the frame for decision‐making. Thus, for example, the prevention of childhood obesity, although valuable in itself, does not have a significant impact in preventing the cost of diabetes for about 40 years, whereas a marked reduction in overweight/adults with obesity by getting adults to lose at least 15% of their weight leads to a rapid economic gain as set out by the UK’s Chief Scientist’s inquiry into obesity [77]. This finding has been amplified by Lean and others’ new demonstration of the marked impact on diabetes of inducing at least a 15% weight loss with continuous very‐low‐calorie diets – 85% of recently diagnosed patients with diabetes return their glucose status to near normal levels [78].

      Although obesity has been recognized for millennia as a clinical syndrome, it is only since the 1980s that there has been an explosion of cases worldwide linked to dramatic industrial developments. The burden for physicians is overwhelming, and overweight and obesity per se now constitutes a grave economic and medical burden. This is why radical approaches are now needed to reduce the clinical consequences.

      1 1. Bray GA. Historical framework for the development of ideas about obesity. In: Bray GA, Bouchard C, James WPT (eds) Handbook of Obesity, 1st edn. New York: Marcel Dekker Inc., 1997:1–30.

      2 2. Rasmussen N. Fat in the Fifties: America’s First Obesity Crisis. Baltimore: Johns Hopkins University Press, 2019.

      3 3. James WPT (Compilor). Research on Obesity. A Report of the Department of Health and Social Security/Medical Research Council Group. London: HMSO, 1976.

      4 4. Black D, James WPT, Besser GM, et al. Obesity. A report of the Royal College of Physicians. J R Coll Phys Lond 1983; 17(1):5–65.

      5 5. World Health Organization (WHO). Obesity: Preventing and Managing the Global Epidemic. Report of a WHO Consultation: WHO Technical Report Series 894. Geneva: World Health Organization, 2000.

      6 6. James WPT, Ferro‐Luzzi A, Waterlow JC. Definition of chronic energy deficiency in adults. Report of a Working Party of the International Dietary Energy Consultative Group. Eur J Clin Nutr 1988; 42:969–81.

      7 7. Ferro‐Luzzi A, Sette S, Franklin M, James WP. A simplified approach of assessing adult chronic energy deficiency. Eur J Clin Nutr 1992; 46(3):173–86.

      8 8. WHO expert consultation (held in Singapore). Appropriate body‐mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004; 363:157–63.

      9 9. Chen CM. Overview of obesity in Mainland China. Obes Rev 2008; 9(Suppl 1):14–21.

      10 10. Willett WC, Dietz WH, Colditz GA. Guidelines for healthy weight. N Engl J Med 1999; 341:427–34.

      11 11. Komlos J, Brabec M. The trend of mean BMI values of US adults, birth cohorts 1882–1986 indicates that the obesity epidemic began earlier than hitherto thought. Am J Hum Biol 2010; 22(5):631–8.

      12 12. Office of Population Censuses and Surveys. OPCS Monitor ref. SS 81/1. 1981.

      13 13. Norton K, Dollman J, Martin M, Harten N. Descriptive epidemiology of childhood overweight and obesity in Australia: 1901–2003. Int J Pediatr Obes 2006; 1(4):232–8.

      14 14. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000; 320:1240.

      15 15. Cole TJ, Lobstein T. Extended international (IOTF) body mass index cut‐offs for thinness, overweight and obesity. Pediatr Obes 2012; 7:284–94.

      16 16. Finucane MM, Stevens GA, Cowan MJ, et al. Global burden of metabolic risk factors of chronic diseases collaborating group (body mass index). National, regional, and global trends in body‐mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country‐years and 9.1 million participants. Lancet 2011; 377:557–67.

      17 17. NCD Risk Factor Collaboration. Worldwide trends in body‐mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population‐based measurement studies in 128·9 million children, adolescents, and adults. Lancet 2017; 390:2627–42.

      18 18. OECD. Obesity update. 2017, Available from: www.oecd.org/health/obesity‐update.htm

      19 19. Cecchini M. Heavy Burden of Obesity: The Economics of Prevention. A Quick Guide for Policy Makers. Paris: OECD, 2019.

      20 20. Foresight. Tackling Obesities: Future Choices. UK Government Office of Science, 2007, Available from: www.foresight.gov.uk

      21 21. The McKinsey Global Institute. Overcoming obesity: an initial economic analysis. In: R. Dobbs, C. Sawers, F. Thompson, et al. (eds) A Discussion Paper. London: McKinsey Global Institute, 2014.

      22 22. UK Government. National Statistics. Health Survey for England. Findings and Trend tables. Available from: https://www.gov.uk/government/statistics/health‐survey‐for‐england‐2016‐findings‐and‐trend‐tables. 2016.

      23 23. Jaacks LM, Vandevijvere S, Pan A, et al. The obesity transition: stages of the global epidemic. Lancet Diabetes Endocrinol 2019; 7(3): 231–40.

      24 24. NCD Risk Factor Collaboration. Rising rural body‐mass index Is the main driver of the global obesity epidemic in adults. Nature 1999; 569(7755):260–64.

      25 25. Vague J. La différentiation sexuelle, facteur detérminant des forme de l’obésité. La Presse Médicale1947; 30:339–40.

      26 26. Han TS, van Leer EM, Seidell JC, Lean ME. Waist circumference action levels in the identification of cardiovascular risk factors: prevalence study in a random sample. BMJ 1995; 311:1401–5.

      27 27. SIGN. The Scottish Intercollegiate Guidelines Network [SIGN]: Obesity in Scotland: Integrating Prevention with Weight Management. Edinburgh: Royal College of Physicians, 1996, Available from: http://www.sign.ac.uk

      28 28. National Institutes of Health. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults: The Evidence Report. Washington, DC: US Department of Health and Human Services, 1998.

      29 29. Yusuf S, Hawken S, Ounpuu S, et al. Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case‐control study. Lancet 2005; 366(9497):1640–9.

      30 30. Huxley R, James WP, Barzi F, et al. Ethnic comparisons of the cross‐sectional relationships between measures of body size with diabetes and hypertension. Obes Rev 2008;(suppl 1):53–61.

      31 31. Garnett SP, Baur LA, Cowell CT. Waist‐to‐height ratio: a simple option for determining excess central adiposity in young people. Int J Obes 2008; 32(6):1028–30.

      32 32. McKeigue PM, Shah B, Marmot MG. Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet 1991; 337:382–6.

      33 33. Misra A, Sharma R, Pandey RM, Khanna N. Adverse profile of dietary