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Clinical Obesity in Adults and Children


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thus sedentary leisure time and reduced the need to leave home for entertainment. Life at home has also been transformed by new approaches to food preparation with microwaves, dishwashers, washing machines, etc. becoming a routine addition to kitchen hardware. It is regularly noted that with supermarkets providing ready‐to‐cook meals, the preparation time for meals has reduced from 2 to 3 hours to as little as 20 minutes.

      Obtaining independent analyses of secular changes in energy expenditure is not easy, and if one simply relies on questionnaires, then sometimes total physical activity does not seem to have changed over time, e.g. in Finland [58]; but in China, there has been a marked decrease in physical activity [59], and the overall conclusions are that there has been a substantial decline in physical activity demands [60]. Secular studies in Norwegian children studied with accelerometer readings in 2005 and then again up to 2012 showed there was a consistent reduction in more intense physical activity even within this short time interval. In addition, there was an age‐related decline in physical expenditure as children became adolescents [61].

Schematic illustration of the principal factors leading to the obesity epidemic.

      Now, as well as the secular decline in physical activity, there is a concomitant reduction in activity as people age. This was shown most vividly in the Baltimore aging studies, where one can recalculate the data on the energy needs of men first when they were 25 years of age and then when the same men were aged 70. If one applies the energetic analyses to the fall in activity and tissue metabolism as the muscle mass slowly declines but adjust the data so that they were the same body weight, then the overall reduction in energy output amounts to a fall of 2100 per day. This means that over the 45 years the falling output is equivalent to an annual average reduction of nearly 50 kcal/day. So in effect the Baltimore men’s food intake needed to fall by nearly 50 kcals each day with further equivalent falls in daily intake each year decade after decade to avoid putting on weight as they age [62]. If extra food is eaten, then weight gain occurs, and the classic analyses suggest that about 20–25% of this is lean tissue which then contributes to increasing the maintenance energy requirement.

      This interaction of secular falls in demand for physical activity, together with the natural reduction in physical activity with aging, explains why in the 1970s, obesity was mostly confined to older adults. To prevent obesity, the body’s appetite sensing system would need to progressively reduce our food intake as we grow older, and this has become far more difficult with such limited levels of physical activity.

      A revolution in food industrial strategies which increase food intakes

      In the mid‐1980s, one of the authors W.P.T. James was invited by the UK government to join an expert panel examining broad aspects of national industrial policy ranging from financial management to manufacturing and the service sector. The author’s remit was to deal with the food, drink, and agricultural industry. Each member led a team with Delphi exercises involving a variety of experts and industrialists and with workshops held in different parts of the country. Given the extraordinary changes in agriculture and food policy that supported self‐sufficiency during the Second World War [64], the author was alarmed to discover the proportion of food, including fruit and vegetables, that were now imported from abroad. Discussions with the Treasury Ministry revealed that they were more concerned about the balance of trade than the availability and access to quality food for the British public. At that time, food product development and marketing were unsophisticated, but suggestions around introducing new health criteria for food composition with the recently proposed WHO criteria based traffic light labeling of healthy food [65] were viewed with horror as this was an industrial enhancement, not a health promotion exercise. However, behavioral research began to develop rapidly in the United States and Europe, leading to a very sophisticated understanding of human behavior and how to manipulate it. Exceptionally detailed analyses of human reactions in shops around time spent examining foods, their position in relation to the height of customers, the value of big rather than small displays, the huge bonus of stacking special price inducements at the end of aisles, and the degree of price manipulations needed to stimulate buying all became carefully defined features for selling more product. Then they discovered the value of stimulating people’s curiosity and providing unexpected stimuli for purchases at all hours of the day and night through the provision of food and drinks in machines or other facilities wherever people might pass or congregate. A multiplicity of flavors in a variety of products encourages greater consumption as using just one flavor leads to what Rolls termed “sensory‐specific satiety.” [66]. Then with the discovery of the range of molecular olfactory receptors for different flavors [67] came the special development of food and drinks with specifically added flavors which were known to have a powerful effect on the brain’s pleasure and addictive centers. Author W.P.T. James had a detailed account from a major industrialist of the finding that specific flavors were favored by women in both the follicular or luteal phases of their