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Fundamentals of Pharmacology


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a paper copy of the BNF and find the last drug you discussed or saw in practice.

       Can you locate it?

       What form does it come in?

       What are the side effects?

       Are there any interactions?

       Can it be bought at the supermarket?

      These are some considerations you may have when supporting people with medication. Pharmaceutical reference guides will help you navigate this complex process and support your evidence‐based practice.

      Produced by the Joint Formulary Committee, the BNF is one of the most commonly used and reliable sources of information on medication. It offers comprehensive details on individual medications, groups of medications, uses, side effects and interactions and can assist with decision‐making. The BNF is an essential tool for all practitioners; it is a repository of almost all drugs that are used in British healthcare settings (Young and Pitcher, 2016). The nurse should ensure they are familiar with its use, making it the go‐to guide for any queries regarding drugs. A joint publication of the Royal Pharmaceutical Society and British Medical Association, it is devised to offer all healthcare professionals contemporary information on medications and their uses. The information provided is sourced from summaries of product characteristics for medications, literature, consensus guidelines and peer review and employs a grading system of A–E and levels of evidence to help readers understand the strength of evidence underpinning the associated recommendations given (Joint Formulary Committee, 2019a).

      Paper copy BNF

      Two types of BNF are available for practitioners: the BNF and the BNF for children (BNFc). Ensuring that you use the most appropriate type for your practice area is essential as medications, recommendations, licensing, legislation and monitoring differ for adults and children. The BNF is published in paper copy bi‐annually in September and March and the BNFc is published in paper copy once a year in September. There are electronic versions (as discussed later) which are frequently updated, so it is always advisable to use the electronic version to ensure the most up‐to‐date information is accessed.

      As a health professional you are accountable for using the most up‐to‐date evidence base for your practice. This means ensuring that you only use the current version of the BNF and that which relates to your practice area and patient group. You should consider:

       that previous versions may have outdated information or even sections that have been removed;

       the implications of advising your patient on their medication regimen if the information source you have chosen is out of date. What are the potential risks to the patient? What could this mean for your practice and accountability?

      How to navigate the BNF

      At first glance, the BNF can be overwhelming; however, with a little practice it quickly becomes a fast and reliable way to gather information for yourself, patients and those you work with.

      The current BNF print versions are organised into four main sections:

       front matter

       chapters

       appendices

       back matter.

      Front matter

Text format Information use
Black Information on treatment summary and therapeutic uses
Colour block Information on drug‐specific information

      A general overview of specific patient‐centred considerations is given in relation to prescribing in hepatic (liver) and renal (kidney) failure, as well considerations for pregnancy, elderly and palliative care. Each section has a broad overview followed by specific considerations. For example, in prescribing for palliative care, specific information is provided on pain, wider symptom control and continuous subcutaneous infusions.

      Chapters

      The main body of the BNF is divided into systems chapters (i.e. gastrointestinal system) and follows the same structure.

      Some drugs and chapters have a class monograph. A class monograph includes information that is common to all drugs within a particular class. It is important to read these in conjunction with the drug monograph, which gives information relating to that drug in particular. Class monographs are identified by a flag in a circle image. If the drug you are seeking advice on has an associated class monograph it will be indicated by a tab with a flag symbol and the page number where the class monograph can be found image.

      Access a copy of the current BNF and open the gastrointestinal system chapter. It starts with a clear contents section indicating what can be found in the chapter and is followed by information on the associated diseases, conditions and disorders, treatment summaries and individual medication information. Focusing on constipation, find and read the description of the condition and its associated overview and management.

      The classification of the individual drug is indicated in blue (e.g. Laxatives: Bulk‐forming laxatives) with the drug name and drug monograph sited below. The drug monograph provides comprehensive information on the drug all in one concise section. Pertinent guidance is offered relating to drug action, indications and dose, adjustments and interactions, safety information, contraindications, signposting to the correct section of interactions, side effects and medicinal forms.

      In the example in Figure 2.1, the monograph depicted displays a flag, this indicates that the drug class monograph for Beta‐adrenoceptor blocker (systemic) should be consulted in tandem.

      Within the drug monograph the following are also highlighted:

       Drug classification: may be based on pharmaceutical class – for example, opioids – but may also