Table of Contents
1 Cover
4 Preface
6 Part 1: Foundations of Endocrinology CHAPTER 1: Overview of endocrinology A brief history of endocrinology and diabetes The role of hormones Classification of hormones Control systems regulating hormone production Endocrine disorders CHAPTER 2: Basic cell biology and hormone synthesis Chromosomes, mitosis and meiosis Synthesizing a peptide or protein hormone Synthesizing a hormone derived from amino acids or cholesterol Hormone transport CHAPTER 3: Molecular basis of hormone action Cell‐surface receptors Nuclear receptors CHAPTER 4: Investigations in endocrinology and diabetes Pre‐analytical requirements for accurate endocrine testing Laboratory assay platforms Reference ranges Static and dynamic testing Cell and molecular biology as diagnostic tools Imaging in endocrinology
7 Part 2: Endocrinology – Biology to Clinical Practice CHAPTER 5: The hypothalamus and pituitary gland Embryology and anatomy Pituitary tumours The hypothalamus The hypothalamic–anterior pituitary hormone axes The anterior pituitary hormones Hypopituitarism Hormones of the posterior pituitary CHAPTER 6: The adrenal gland The adrenal cortex The adrenal medulla CHAPTER 7: Reproductive endocrinology Embryology of the reproductive organs The male reproductive system The female reproductive system Pubertal disorders Subfertility CHAPTER 8: The thyroid gland Embryology Anatomy and vasculature Thyroid hormone biosynthesis Circulating thyroid hormones Function of thyroid hormones Thyroid function tests Clinical disorders CHAPTER 9: Calcium and metabolic bone disorders Calcium Hormones that regulate calcium Clinical disorders of calcium homeostasis Bone health and metabolic bone disease Clinical conditions of bone metabolism Vitamin D deficiency, osteomalacia and rickets CHAPTER 10: Pancreatic and gastrointestinal endocrinology and endocrine neoplasia Pancreatic endocrinology Gastrointestinal endocrinology and associated clinical conditions Endocrine tumour predisposition syndromes Tumours with ectopic hormone production Hormone‐sensitive tumours Other tumours relevant to endocrinology
8 Part 3: Diabetes and Obesity CHAPTER 11: Overview of diabetes A brief history of diabetes and its classification Classification of diabetes Diagnosis of diabetes Insulin