Glucagon CHAPTER 12: Type 1 diabetes What is type 1 diabetes? Epidemiology Pathogenesis Aetiology Clinical features Diagnosis Management of type 1 diabetes Acute metabolic emergencies CHAPTER 13: Type 2 diabetes Epidemiology Pathophysiology Prognosis Clinical features Prevention of diabetes Screening for diabetes Management of type 2 diabetes CHAPTER 14: Complications of diabetes Introduction Microvascular complications Pathology of microvascular complications Pathogenesis of microvascular complications Clinical features of microvascular complications Diabetes‐related kidney disease Neuropathy The diabetic foot Genitourinary and sexual problems of diabetes Atherosclerotic cardiovascular disease Heart failure Cancer Non‐alcoholic fatty liver disease Gastro‐intestinal tract Bone and Joint Skin disorders Psychological and psychiatric sequelae of diabetes Diabetes and pregnancy Social sequelae of diabetes Organization of diabetes care CHAPTER 15: Obesity Introduction What is obesity? The health and social consequences of overweight and obesity Regulation of body weight The causes of obesity Genetic factors Environmental changes Prevention of obesity Management of the individual with obesity Conclusions
9 Index
List of Tables
1 Chapter 1Table 1.1 Nobel prizewinners in endocrinology and diabetes or those whose dis...Table 1.2 The endocrine organs and their hormones*
2 Chapter 2Table 2.1 Definition and classification of enzymes
3 Chapter 3Table 3.1 Use of different G‐protein α‐subunits by various hormone signalling...Table 3.2 Examples of modifications to hormones, their precursors or metaboli...Table 3.3 Defects in nuclear hormone signallingTable 3.4 Examples of important transcription factors required for the develo...
4 Chapter 4Table 4.1 Endocrine reference ranges
5 Chapter 5Table 5.1 Summary of anatomy and function of the hypothalamic nucleiTable 5.2 Hormone‐secreting cell types of the anterior pituitaryTable 5.3 Cranial nerves in the cavernous sinusTable 5.4 Dynamic tests of growth hormone (GH) statusTable 5.5 Treatments of acromegalyTable 5.6 Investigation and management of diabetes insipidus (DI).
6 Chapter 6Table 6.1 Alternative names in common usage for steroidogenic enzymesTable 6.2 Dexamethasone suppression testsTable 6.3 The effects of catecholaminesTable 6.4 Genes and associated PPGL syndromes
7 Chapter 7Table 7.1 Advantages and disadvantages for different routes of administration...Table 7.2 GynaecomastiaTable 7.3 Different phases of ovarian function and their effectsTable 7.4 Approaching amenorrhoea with absent oestrogenTable 7.5 Approach to amenorrhoea with endogenous oestrogen productionTable 7.6 Treatment of PCOSTable 7.7 Precocious pubertyTable 7.8 An approach to subfertility
8 Chapter 8Table 8.1 Interpretation of thyroid function testsTable 8.2 Symptoms, signs and examination of thyroid eye diseaseTable 8.3 Thyroid malignancy
9 Chapter 9Table 9.1 Comparative actions of vitamin D, parathyroid hormone (PTH) and cal...Table 9.2 Diagnostic criteria for osteoporosis on DEXATable 9.3 Drugs used to prevent bone demineralisation