Группа авторов

Metabolic Syndrome Consequent to Endocrine Disorders


Скачать книгу

in patients with hypopituitarism and growth hormone deficiency. Used with permission from Lancet Oncology, reference number 4177570097030 [104].

      Glucose Metabolism and Insulin Resistance in GHD and Responses to GHRT

      Advancing age, BMI, family history of diabetes, female sex, etiology of hypopituitarism (diagnosis of craniopharyngioma, pituitary adenoma, IGHD), and increasing number of components of MetS have been identified as relevant risk factors for diabetes in various studies reported so far [6, 16, 48, 49]. Data regarding the prevalence of diabetes mellitus in GH treated versus untreated patients with adult-onset of hypopituitarism are still lacking as well as prospective randomized controlled trials with life style and/or pharmacological interventions aiming to decrease visceral obesity and insulin resistance in these patients.

      Changes in Body Composition: Visceral Obesity in GHD and Response to GHRT

      Hypertension, Vascular Changes, Inflammatory Cardiovascular Risk Markers, and Hypofibrinolysis in Patients with GHD