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Salivary Gland Pathology


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      Library of Congress Cataloging‐in‐Publication Data applied for [ISBN: 9781119730187]

      Cover image:

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      Contributors

      Eric R. Carlson, DMD, MD, EdM, FACS

      Department of Oral and Maxillofacial Surgery, University of Tennessee Graduate School of Medicine, University of Tennessee Cancer Institute, Knoxville, TN, USA

      Robert A. Ord, BDS, MB BCh (Hons), FRCS, FACS, MS, MBA

      Department of Oral and Maxillofacial Surgery, University of Maryland Medical Center, Greenbaum Cancer Institute, Baltimore, MD, USA

      Katherine George, BDS, BSc, MBBS, MFDS RCS (Eng), FRCS (OMFS)

      Oral and Maxillofacial Surgeon, Kings College Hospital NHS Foundation Trust, Denmark Hill, London, UK

      Pradeep Jacob, MD, MBA

      Private Practice of Radiology, Chattanooga, TN, USA

      Joseph Kelley, MD, PhD

      Director of Clinical Research, GenesisCare USA of North Carolina

      Lara Kujtan, MD, MSc

      Department of Medicine, University of Missouri at Kansas City, Kansas City, MO, USA

      John D. Langdon, FKC, MB BS, BDS, MDS, FDSRCS, FRCS, FMedSci

      Department of Maxillofacial Surgery, King’s College, London, England

      J. Michael McCoy, DDS

      Departments of Oral and Maxillofacial Surgery, Pathology, and Radiology, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA

      Mark McGurk, BDS, MD, FRCS, DLO, FDS, RCS

      Head and Neck Academic Center, Department of Head and Neck Surgery, University College London Hospital, London, UK

      Max Ofori, MD

      Division of Radiation Oncology, University of Tennessee Medical Center, Knoxville, TN, USA

      John J. Sauk, DDS, MS, FAAAS, FAHNS

      School of Dentistry, University of Louisville, Louisville, KY, USA

      Janikiraman Subramanian, MD

      Department of Medicine, Thoracic Oncology and Center for Precision Oncology, Saint Luke’s Cancer Institute, University of Missouri at Kansas City, Kansas City, MI, USA

      Randy Todd, DMD, MD, DSc

      Private Practice of Oral and Maxillofacial Surgery (retired), Peabody, MA, USA

      Michael D. Turner, DDS, MD, FACS

      Division of Oral and Maxillofacial Surgery, Mount Sinai Hospital, Icahn Mount Sinai School of Medicine, New York, NY, USA

      Foreword First Edition

      The mention of “head and neck cancer” immediately connotes the sobering realities and potentials of oral squamous cell carcinoma. Left to secondary recollection and awareness is the significance of salivary gland malignancy. The same can be said for the general perception of benign salivary neoplasia. In this brilliant new textbook, authors Carlson and Ord correct these notions, focusing proper emphasis on the group of diseases which, in their malignant form, represent some three percent of all North American head and neck tumors, affecting a minimum of 2500 victims per year.

      One marvels at the dedication, energies, and resources – to say nothing of the expertise – mustered to produce a volume of this depth and expanse. While almost forty percent of the effort is directed toward the vitally significant elements of classification, diagnosis, and clinical care of neoplasia, there is more – much more – here, for both the training and practicing readerships. The whole array of salivary gland dysfunctions is marvelously displayed in meaningful clinical color, in easily grasped sketches and graphs, and in well‐chosen descriptive imaging. From the mandatory fundaments for such an undertaking – John Langdon's discourse on macro‐ and microanatomy, Pradeep Jacob's presentation on imaging diagnostics (45 pages!), John Sauk's explanations of current classification and staging of tumors – to the surgical demonstrations of pathology, anatomy, and technique, the visual material is extraordinary.

      What are the vagaries in defining the SMAS layer, can cell type be distinguished on the basis of imaging alone, what influence do genomics and biomarkers have in clinical classification, does contemporary understanding explain the etiology of mucous escape phenomena? Up‐to‐date propositions on such topics occupy these chapters. Clinical challenges, traditional and new, e.g., transection of ducts and nerves, intraductal micromanipulations, salivary diagnostics – they're all here, presented in clear, expansive, prose (28 pages of information on sialolithiasis alone!). The detriments of age and metabolic disorder on gland function, the genesis of non‐salivary tumors inside the glands, and the lodging of metastatic disease within their confines receive emphasis in these pages. So do the presence of aberrant glands and the esoteric transplantation of salivary tissue in the management of xerophthalmia.

      The Textbook and Color Atlas of Salivary Gland Pathology is authoritative. Its authors do not write anecdotally, but from the combined experience of decades which has elevated them both to international recognition in the field of head and neck neoplasia. Their clinical material here presented represents volumes in the operating room, and the comprehensive bibliographies in each of the text's chapters testify to the authors' awareness of their topic and their world‐views. Eric Carlson displays the fruits of his earlier endeavors in Pittsburgh, Detroit, and Miami, and speaks now from his position as Professor and Chairman in the Department of Oral and Maxillofacial Surgery at the University of Tennessee Graduate School of Medicine in Knoxville. Robert Ord established his worthy reputation in Britain before resettling himself in Baltimore on the western shores of the Atlantic some 20 years ago, where he now serves as Professor and Chairman of the Department of Oral and Maxillofacial Surgery at the University of Maryland. Theirs is the first time in this domain engineered authoritatively by oral and maxillofacial surgeons, and does honor to their colleagues and forebears in the specialty who have toiled in the vineyards of salivary gland pathology. Neither in design nor execution, however, is their marvelous achievement directed to a parochial audience. Rather, surgeons or clinicians of whatever ilk will offer the authors a nod of appreciation in benefitting from this text.

      Probably, one day, an expansion of this work will be written; and, undoubtedly, Carlson and Ord will write it.

      R. Bruce MacIntosh, DDS

      Detroit

      June 2008

      Foreword Second Edition

      Casual students of surgery