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Salivary Gland Pathology


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of intrauterine life, the gland is completely canalized. Although not embryologically a bilobed structure, the parotid comes to form a larger (80%) superficial lobe and a smaller (20%) deep lobe joined by an isthmus between the two major divisions of the facial nerve. The branches of the nerve lie between these lobes invested in loose connective tissue. This observation is vital in the understanding of the anatomy of the facial nerve and surgery in this region (Berkovitz et al. 2003).

      The parotid is the largest of the major salivary glands. It is a compound, tubuloacinar, merocrine, exocrine gland. In the adult, the gland is composed entirely of serous acini.

      Source: Published with permission, Martin Dunitz, London, Langdon JD, Berkowitz BKB, Moxham BJ, editors, Surgical Anatomy of the Infratemporal Fossa. DOI: 10.1002/9781118949139.ch1.

      The shape of the parotid gland is variable. Often it is triangular with the apex directed inferiorly. However, on occasion, it is essentially of even width and occasionally it is triangular with the apex superiorly. On average, the gland is 6 cm in length with a maximum of 3.3 cm in width. In 20% of subjects, a smaller accessory lobe arises from the upper border of the parotid duct approximately 6 mm in front of the main gland. This accessory lobe overlies the zygomatic arch.

      The parotid capsule develops relatively late after the lymphoid tissue develops within the mesenchyme of the gland (Goldenberg et al. 2000). For this reason, the lymph nodes associated with the parotid gland are intraglandular as opposed to the extraglandular lymph nodes associated with the submandibular and sublingual salivary glands, in which the capsule forms earlier in their development.

      Where the deep aspect of the superficial lobe overlies branches of the facial nerve, the capsule becomes very thin or even nonexistent, resulting in acinar tissue lying in direct contact with the nerve fibers.

Photo depicts the parotid gland and associated structures.

      Source: Published with permission, Martin Dunitz, London, Langdon JD, Berkowitz BKB, Moxham BJ, editors, Surgical Anatomy of the Infratemporal Fossa. DOI: 10.1002/9781118949139.ch1.

      The superficial surface of the gland is covered by skin and platysma muscle. Some terminal branches of the great auricular nerve also lie superficial to the gland. At the superior border of the parotid, lie the superficial temporal vessels with the artery in front of the vein. The auriculotemporal branch of the mandibular nerve runs at a deeper level just behind the superficial temporal vessels.

      The branches of the facial nerve emerge from the anterior border of the gland. The parotid duct also emerges to run horizontally across the masseter muscle before piercing the buccinator muscle anteriorly to end at the parotid papilla. The transverse facial artery (a branch of the superficial temporal artery) runs across the area parallel to and approximately 1 cm above the parotid duct. The anterior and posterior branches of the facial vein emerge from the inferior border.

      The deep (medial) surface of the parotid gland lies on those structures forming the parotid bed. Anteriorly the gland lies over the masseter muscle and the posterior border of the mandibular ramus from the angle up to the condyle. As the gland wraps itself around the ramus, it is related to the medial pterygoid muscle at its insertion on to the deep aspect of the angle. More posteriorly, the parotid is molded around the styloid process and the styloglossus, stylohyoid, and stylopharyngeus muscles from below upwards. Behind this, the parotid lies on the posterior belly of the digastric muscle and the sternocleidomastoid muscle. The digastric and the styloid muscles separate the gland from the underlying internal jugular vein, the external and internal carotid arteries and the glossopharyngeal, vagus, accessory, and hypoglossal nerves and the sympathetic trunk.

Schematic illustration of the mandibulo-stylohyoid ligament.

      Facial Nerve