form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.
The right of Alan J. Sinclair, John E. Morley, Bruno Vellas, Matteo Cesari, and Medha Munshi to be identified as the authors of the editorial material in this work has been asserted in accordance with law.
Registered Office(s) John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, USA John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK
Editorial Office 9600 Garsington Road, Oxford, OX4 2DQ, UK
For details of our global editorial offices, customer services, and more information about Wiley products visit us at www.wiley.com.
Wiley also publishes its books in a variety of electronic formats and by print‐on‐demand. Some content that appears in standard print versions of this book may not be available in other formats.
Limit of Liability/Disclaimer of Warranty The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting scientific method, diagnosis, or treatment by physicians for any particular patient. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.
Library of Congress Cataloging‐in‐Publication Data applied for
HB: 9781119484202
Cover Design: Wiley
Cover Images: © Callista Images/Getty Images, © Westend61/Getty Images, © Getty Images, Patchakorn
Phom‐in/iStockphoto/Getty Images, Westend61/Getty Images, © Luis Alvarez/Getty Images
About the Editors
Alan Sinclair
Professor Alan J. Sinclair is an international expert in diabetes and clinical gerontology and established the Foundation for Diabetes Research in Older People at Diabetes Frail. He is a former professor of medicine at the University of Bedfordshire and former dean at the Bedfordshire & Hertfordshire Postgraduate Medical School. He has provided advice for the UK NICE organisation, British Geriatrics Society, Diabetes UK, ABCD, Joint British Diabetes Societies, Care Quality Commission (CQC), and UK Government Department of Health on matters relating to diabetes in older people. Dr Sinclair has been designated a WHO Expert in Diabetes and has for several years been a member of a World Expert Group on Frailty/Clinical Consortium on Healthy Ageing of the WHO. He was awarded the Presidential Medal of the IAGG in 2013 for services to older people and diabetes.
John Morley
Dr John E. Morley is a professor of internal medicine in the Division of Geriatric Medicine at the Saint Louis University School of Medicine (St Louis, Missouri, USA). He has been the principal investigator for the Missouri Illinois Gateway Geriatric Center or the Geriatric Workforce Enhancement Program for the past 27 years. He helped create the Saint Louis University Health Resource Center, a student‐run free health clinic providing healthcare and social services for underserved and uninsured individuals. The clinic has grown to serve children and adults and developed many specialty clinics, such as women’s wellness and nutrition. Clinically, he focuses on diabetes, nutrition, frailty, and cognitive assessment. He is a sought‐after speaker nationally and internationally on multiple topics, including ’Aging Successfully’.
Bruno Vellas
Bruno Vellas is the chair of the Gérontopôle & Department of Geriatric Internal Medicine at the Toulouse University Hospital and is a member of INSERM UMR 1027. He is the founder of the Gérontopôle to develop innovation and research for older adults. He is an adjunct professor at the Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA . He has been the chair of the WHO Collaborating Center for Frailty, Clinical Research, and Geriatric Training since September 2017. He is a IAGG past president, he is president of the Scientific Committee of the French National ‘Great Age’ and principal investigator of the INSPIRE program in the field of gerosciences.
Matteo Cesari
Matteo Cesari, MD, PhD is associate professor of geriatrics at the Università di Milano and head of the Geriatric Unit at the IRCCS Istituti Clinici Scientifici Maugeri (Milan, Italy). Dr Cesari previously worked at Wake Forest University (Winston Salem, North Carolina, USA), the University of Florida‐Institute on Aging (Gainesville, Florida, USA), and the Centre Hospitalier Universitaire de Toulouse (Toulouse, France). Dr Cesari is editor in chief of The Journal of Frailty & Aging and senior associate editor of the Journal of the American Medical Directors Association (JAMDA).
His research activities are focused on the frailty condition and strategies aimed at preventing the disabling cascade. Dr Cesari’s scientific projects have been funded by public agencies (including the US National Institute on Aging, the French Agence Nationale de Recherche, and the Italian Ministry of Health) as well as private institutions (e.g. the Swiss Bridge Foundation).
Dr Cesari has published more than 460 articles in peer‐reviewed scientific journals and is among the worldwide Highly Cited Researchers. Dr Cesari actively collaborates with the World Health Organization (WHO) on the themes of healthy ageing and integrated care for older persons. He is member of the WHO Clinical Consortium on Healthy Ageing.
Medha Munshi
Dr Medha Munshi is an associate professor of medicine at the Harvard Medical School and is the founding president of the International