2.92. Cooperative catalysis with CPA and Pd(II) complex (a) (), a...Scheme 2.93. Cooperative catalysis with CPA and Rh2(OAc)4.
3 Chapter 3Figure 3.1. General catalytic cycle for Brønsted base catalysis.Figure 3.2. Relationship between basicity of uncharged organobases and acidi...Scheme 3.1. Enantioselective addition of aryl thiols to cyclic enones cataly...Figure 3.3. Cinchona alkaloids and derivatives.Figure 3.4. Chiral acid–base bifunctional catalysts.Scheme 3.2. Enantioselective addition of malonates to nitroalkenes catalyzed...Figure 3.5. Proposed mechanism of the bifunctional amine‐thiourea catalyzed ...Scheme 3.3. Enantioselective addition of nitromethane to chalcone derivative...Scheme 3.4. Enantioselective addition of β‐ketoesters to nitroalkenes cataly...Scheme 3.5. Enantioselective addition of β‐ketoesters to nitroalkenes cataly...Figure 3.6. Transition‐state model of Michael addition catalyzed by 1f.Scheme 3.6. Enantioselective addition of pyrazoleamides 3 to nitroalkenes ca...Scheme 3.7. Enantioselective aldol reaction of malonic acid half thioesters Scheme 3.8. Synthesis of oxindoles possessing adjacent tetrasubstituted ster...Scheme 3.9. Enantioselective aldol reaction of fluorinated malonic acid half...Figure 3.7. N‐Heterocyclic compounds used as a pronucleophile.Scheme 3.10. Enantioselective addition of thiazolones 8 to nitroalkenes cata...Scheme 3.11. Enantioselective addition of MAC reagents 11 to enones catalyze...Scheme 3.12. Enantioselective addition of glyoxylate cyanohydrins to imines ...Scheme 3.13. α‐Functionalization of 2‐alkyl azaarene N‐oxides 13. Source: Ba...Scheme 3.14. Enantioselective Michael addition of barbituric acid derivative...Scheme 3.15. Enantioselective cycloetherification via oxa‐Michael addition c...Scheme 3.16. Enantioselective synthesis of spiroketals.Scheme 3.17. Enantioselective synthesis of tetrahydropyrans with two stereog...Scheme 3.18. Enantioselective intramolecular oxa‐Michael addition of α,β‐uns...Scheme 3.19. Enantioselective intramolecular oxa‐Michael addition of in situ...Scheme 3.20. Enantioselective intramolecular aza‐Michael addition of enamine...Scheme 3.21. One‐pot catalytic enantioselective synthesis of 2‐pyrazolines....Scheme 3.22. Enantioselective addition of thioacids to trisubstituted nitroa...Scheme 3.23. Enantioselective addition of thiols to in situ generated ortho‐...Scheme 3.24. Enantioselective Michael/cyclization reaction sequence catalyze...Scheme 3.25. Enantioselective Tamura cyclization catalyzed by 2w.Scheme 3.26. Enantioselective formal [3+2] cycloaddition of cyclopropyl keto...Scheme 3.27. Enantioselective synthesis of benzazocinones. Source: Based on ...Scheme 3.28. Enantioselective synthesis of axially chiral 4‐arylpyridine der...Scheme 3.29. Enantioselective synthesis of atropoisomeric furans based on th...Scheme 3.30. Intramolecular [4+2] cycloaddition between in situ generated vi...Scheme 3.31. Enantioselective Strecker reaction catalyzed by 21. Source: Bas...Scheme 3.32. Enantioselective Strecker reaction catalyzed by 22a.Figure 3.8. Proposed reaction mechanism.Scheme 3.33. Enantioselective protonation catalyzed by 22b.Scheme 3.34. Enantioselective isomerization of 3‐alkynoate catalyzed by 22b....Scheme 3.35. Enantioselective Michael addition of glycine imines to acrylate...Scheme 3.36. Enantioselective reactions of 5H‐oxazol‐4‐ones as a pronucleoph...Scheme 3.37. Enantioselective addition of phenols to nitroalkenes catalyzed ...Scheme 3.38. Solvent‐dependent enantiodivergent Mannich‐type reaction cataly...Scheme 3.39. Enantioselective addition of β‐ketoesters to nitroalkenes catal...Scheme 3.40. Enantioselective reactions catalyzed by 26.Scheme 3.41. Enantioselective α‐hydroxylation of β‐ketoesters catalyzed by 2...Scheme 3.42. Desymmetrization of meso‐aziridines with thiols catalyzed by 28Figure 3.9. Axially chiral guanidine catalysts.Scheme 3.43. Enantioselective reactions of furanones as a pronucleophile cat...Scheme 3.44. Enantioselective amination of β‐dicarbonyl compounds with azodi...Figure 3.10. Chiral cyclopropenimine catalyst.Scheme 3.45. Enantioselective additions of glycine imines catalyzed by 31....Figure 3.11. Mechanistic rationale.Scheme 3.46. Enantioselective [3+2] cycloaddition of glycine imines with 2‐a...Figure 3.12. Chiral bifunctional iminophosphorane (BIMP) catalysts.Scheme 3.47. Enantioselective addition of nitromethane