11:93–112.
15 Kitcher, Philip ( 1997). “Whose Self Is It, Anyway?” The Sciences 37/5, September/October 1997, 58–62.
16 LaBar, Martin (1984). “The Pros and Cons of Human Cloning,” Thought 57: 318–33.
17 Locke, John. An Essay Concerning Human Understanding, (1632–1704)
18 Marquis, Don (1989). “Why Abortion is Immoral,” Journal of Philosophy, 86/4, 183–202. (See also Chapter 4 of this Anthology).
19 Mattachine Society Inc., of New York (1964). “Penalties for Sex Offenses in the United States,” The New York Public Library Digital Collections. https://digitalcollections.nypl.org/items/67116400‐873c‐257c‐e040‐e00a18065646 (Accessed September 17, 2020).
20 Ogonuki, Narumi, et al (2002). “Early death of mice cloned from somatic cells,” Nature, 30, 253–4.
21 Parfit, Derek (1984). Reasons and Persons, Oxford: Clarendon Press.
22 Pew Research Center (2013). “The Global Divide on Homosexuality“, https://www.pewresearch.org/global/2013/06/04/the‐global‐divide‐on‐homosexuality/ (Accessed January 24, 2020.)
23 Pinker, Steven (1997). How the Mind Works. New York: W. W. Norton & Company, Inc.
24 PPRI (2019). “New Landmark Survey of 50 States Finds Broad Support for LGBT Rights Across the United States,” https://www.prri.org/press‐release/new‐landmark‐survey‐of‐50‐states‐finds‐broad‐support‐for‐lgbt‐rights‐across‐the‐united‐states/ (Accessed January 24, 2020.)
25 Rawls, John (1971). A Theory of Justice, Cambridge, MA: Harvard University Press.
26 Robertson, John A. (1994). “The Question of Human Cloning,” Hastings Center Report 24, 6–14.
27 Sinclair, K. D., et al (2016). “Healthy ageing of cloned sheep,” Nature Communications, 26 July, 2016, 1–10.
28 Tooley, Michael, and Plantinga, Alvin (2008). Knowledge of God, Oxford: Blackwell Publishing.
29 Tooley, Michael, Wolf‐Devine, Celia, Devine, Philip E. and Jaggar, Alison M. (2009). Abortion: Three Perspectives, New York: Oxford University Press.
30 Tooley, Michael (1983). Abortion and Infanticide, Oxford: Clarendon Press.
31 ————, (1998). “The Moral Status of the Cloning of Humans,” In James Humber and Robert Almeder (eds.), Biomedical Ethics Reviews: Human Cloning, Humana Press, Totowa, New Jersey, 65–101.
32 ————, (2019). The Problem of Evil, Cambridge: Cambridge University Press.
Note
1 1 Although Kitcher mentions this idea as initially attractive, in the end he rejects it, on the grounds that cloning “interferes with human autonomy” (1997, 61) – a view that I considered, and argued against, in section 3.1.5.
Introduction
Our genes play an important role in what kind of people we are – whether we are, for example, short or tall, healthy or sick, mentally slow or bright; and while there is debate about the extent to which certain characteristics are inherited or the product of our environment, it is difficult to deny that some characteristics at least have a genetic basis. To deny this would, as Jonathan Glover points out in “Questions about Some Uses of Genetic Engineering” amount to thinking “that it is only living in kennels which makes dogs different from cats”.
Genetic manipulation, sometimes also referred to as genetic engineering, involves intervening at the genetic level in order to eliminate, modify, or enhance certain genetic traits or conditions. Recent scientific breakthroughs, including the mapping of the human genome, have added significantly to our understanding of our genes, and provide increasing and unprecedented possibilities for control over our genetic destiny. Should we make use of this knowledge, and to which ends? Should we, for example, use genetic manipulation only to prevent serious genetic disorders, or should we also use it for the enhancement of certain traits and characteristics?
The distinction between gene therapy and gene enhancement is not clear‐cut. While it might be agreed that increasing the height a boy is expected to reach at maturity from 170 cm to 190 cm is a form of enhancement, what if we are seeking to increase his expected height from 150 cm to 170 cm? The same appears to be true when we are looking at a trait such as intelligence. Increasing a person’s IQ by 20 points from 110 to 130 would generally be considered enhancement, but would raising her IQ from 90 to 110 be therapy or of enhancement? The answer ultimately depends, David B. Resnik argues in “The Moral Significance of the Therapy–Enhancement Distinction in Human Genetics,” on contested philosophical distinctions, such as the distinctions between health and disease, and normality and abnormality.
Despite some fuzziness at the margins, we do, however, often have a plausible understanding of where the boundary between therapy and enhancement should be drawn. The next question is whether this boundary is morally significant. Again, many people think the answer is “yes.” They take the view that gene therapy, as an extension of the conventional goals of medicine, is morally acceptable, while enhancement is morally problematic. But are the arguments in support of the ethical significance of these distinctions sound?
Some people reject positive genetic engineering on the grounds of risk; but is risk – even significant risk – a sufficient reason to rule out all genetic interventions? Jonathan Glover argues that the fact that a practice involves risks is not sufficient to show that it is morally wrong, or should be banned. In some cases, the dangers of not proceeding might be greater than the dangers of proceeding selectively and cautiously. Moreover, would considerations of risk be a reason against all positive interventions, or against only some of them? And would it be a reason against positive or enhancing genetic interventions only, or also a reason against therapeutic or negative interventions?
Arguments about risk are important, but do not go to the heart of the objections to genetic engineering. Even if gene therapy could be shown to be relatively safe, one oft‐heard objection – that it involves “playing God” – would remain. But this objection, as Glover and others argue, is unpersuasive. Taken literally, it obviously will not appeal to non‐believers; and, if understood metaphorically as a prohibition on interfering with “God’s creation,” that is, with nature, it would seem to rule out not only all genetic engineering (whether positive or negative), but all other medical interventions as well.
A more plausible way of understanding the “playing God” argument might be to see it as an objection to eugenic schemes, where, as Glover puts it, necessarily fallible people with limited horizons are making God‐like decisions to improve the human race. Past eugenic programs in Europe (and particularly in Nazi Germany), Great Britain, and the United States continue to cast a dark shadow over contemporary genetics. These programs were widely associated with a variety of often highly questionable coercive government schemes intended to “improve” the gene pool. The question of whether positive genetic engineering is morally acceptable must, however, Glover argues, be separated from the question of whether particular state‐controlled eugenic programs are acceptable. One might think that it is wrong for state authorities to decide who should and should not be able to have children,